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ACS Chemical Biology|September 28, 2021
Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and ProteinsJohn S Coukos, Raymond E Moellering
Current Opinion in Chemical Biology|March 9, 2020
Interaction profiling methods to map protein and pathway targets of bioactive ligandsJun X Huang, John S Coukos, Raymond E Moellering
Analytical Chemistry|June 18, 2016
Profiling Reactive Metabolites via Chemical Trapping and Targeted Mass SpectrometryJae Won Chang, Gihoon Lee, John S Coukos, et al.
Biochemistry|October 26, 2023
PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase FunctionJohn S Coukos, Chris W Lee, Kavya S Pillai, et al.
ACS Chemical Biology|December 23, 2022
Widespread, Reversible Cysteine Modification by Methylglyoxal Regulates Metabolic Enzyme FunctionJohn S Coukos, Chris W Lee, Kavya S Pillai, et al.
International Urology and Nephrology|November 22, 2024
Organ-confined prostate cancer with negative surgical margins in an entirely-embedded radical prostatectomy is essentially non-lethal-a retrospective single-institutional study of 520 patientsWendy Luo, Sarah Mae Lammert, John S Coukos, et al.
Journal of the American Chemical Society|September 17, 2019
Versatile Peptide Macrocyclization with Diels-Alder CycloadditionsJeffrey E Montgomery, Justin A Donnelly, Sean W Fanning, et al.
Nature Biotechnology|October 27, 2022
Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domainsThomas E Speltz, Zeyu Qiao, Colin S Swenson, et al.
Nature|October 17, 2018
A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signallingMichael J Bollong, Gihoon Lee, John S Coukos, et al.
Cancer Discovery|January 30, 2023
LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung AdenocarcinomaBenjamin D Stein, John R Ferrarone, Eric E Gardner, et al.
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