Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

John Saunders

Showing results (231-240 of 276) with videos related to

Pageof 28
Sort By:
Bioorganic & Medicinal Chemistry Letters|August 1, 2008
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical propertiesColin F Regan, Zhiqiang Guo, Yongsheng Chen, et al.
Journal of Medicinal Chemistry|October 29, 2008
Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic painBrian Dyck, Junko Tamiya, Florence Jovic, et al.
Journal of Medicinal Chemistry|February 20, 2004
Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonistsZhiqiang Guo, Yun-Fei Zhu, Timothy D Gross, et al.
Bioorganic & Medicinal Chemistry|June 5, 2007
Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activityJoe A Tran, Fabio C Tucci, Wanlong Jiang, et al.
Journal of Medicinal Chemistry|September 14, 2013
Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonistsMaris Vilums, Annelien J M Zweemer, Zhiyi Yu, et al.
Journal of Medicinal Chemistry|October 9, 2007
Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexiaChen Chen, Wanlong Jiang, Fabio Tucci, et al.
Surgical Endoscopy|July 21, 2025
Sleeve-to-bypass conversion vs. sleeve-with-adjuvant GLP-1 receptor agonists: an academic multicenter retrospective studyAvery Brown, Helena Sergent, Alexander Hien Vu, et al.
European Journal of Medicinal Chemistry|February 11, 2015
When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as CCR2 antagonistsMaris Vilums, Annelien J M Zweemer, Farhana Barmare, et al.
Journal of Medicinal Chemistry|November 14, 2008
Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (elagolix), a potent and orally available nonpeptide antagonist of the human gonadotropin-releasing hormone receptorChen Chen, Dongpei Wu, Zhiqiang Guo, et al.
Bioorganic & Medicinal Chemistry Letters|September 30, 2004
Small molecule antagonists of the CCR2b receptor. Part 2: Discovery process and initial structure-activity relationships of diamine derivativesWilna J Moree, Ken-ichiro Kataoka, Michele M Ramirez-Weinhouse, et al.
Pageof 28

Showing results (231-240 of 276) with videos related to

Sort By:
Pageof 28
Bioorganic & Medicinal Chemistry Letters|August 1, 2008
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical propertiesColin F Regan, Zhiqiang Guo, Yongsheng Chen, et al.
Journal of Medicinal Chemistry|October 29, 2008
Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic painBrian Dyck, Junko Tamiya, Florence Jovic, et al.
Journal of Medicinal Chemistry|February 20, 2004
Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonistsZhiqiang Guo, Yun-Fei Zhu, Timothy D Gross, et al.
Bioorganic & Medicinal Chemistry|June 5, 2007
Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activityJoe A Tran, Fabio C Tucci, Wanlong Jiang, et al.
Journal of Medicinal Chemistry|September 14, 2013
Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonistsMaris Vilums, Annelien J M Zweemer, Zhiyi Yu, et al.
Journal of Medicinal Chemistry|October 9, 2007
Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexiaChen Chen, Wanlong Jiang, Fabio Tucci, et al.
Surgical Endoscopy|July 21, 2025
Sleeve-to-bypass conversion vs. sleeve-with-adjuvant GLP-1 receptor agonists: an academic multicenter retrospective studyAvery Brown, Helena Sergent, Alexander Hien Vu, et al.
European Journal of Medicinal Chemistry|February 11, 2015
When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as CCR2 antagonistsMaris Vilums, Annelien J M Zweemer, Farhana Barmare, et al.
Journal of Medicinal Chemistry|November 14, 2008
Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (elagolix), a potent and orally available nonpeptide antagonist of the human gonadotropin-releasing hormone receptorChen Chen, Dongpei Wu, Zhiqiang Guo, et al.
Bioorganic & Medicinal Chemistry Letters|September 30, 2004
Small molecule antagonists of the CCR2b receptor. Part 2: Discovery process and initial structure-activity relationships of diamine derivativesWilna J Moree, Ken-ichiro Kataoka, Michele M Ramirez-Weinhouse, et al.
Pageof 28