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John Simms

Showing results (41-50 of 53) with videos related to

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Cell Discovery|July 28, 2016
An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacologyJoseph J Gingell, John Simms, James Barwell, et al.
Biochimica Et Biophysica Acta. Biomembranes|December 31, 2019
Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptorsSarah J Routledge, John Simms, Ashley Clark, et al.
Frontiers in Endocrinology|January 31, 2022
The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor ActivationIan Winfield, Kerry Barkan, Sarah Routledge, et al.
Microbial Biotechnology|October 31, 2019
Preventive antibiotic treatment of calves: emergence of dysbiosis causing propagation of obese state-associated and mobile multidrug resistance-carrying bacteriaDorota A Dobrzanska, Matthew T F Lamaudière, Jessica Rollason, et al.
Molecular Pharmacology|June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screeningCassandra Koole, Denise Wootten, John Simms, et al.
Biochemical Pharmacology|July 15, 2017
Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to GsMichael J Woolley, Christopher A Reynolds, John Simms, et al.
Biochemistry|July 14, 2018
Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) ComplexJohn Simms, Romez Uddin, Thomas P Sakmar, et al.
Biochimica Et Biophysica Acta. Biomembranes|March 4, 2020
Ligand-induced conformational changes in a SMALP-encapsulated GPCRSarah J Routledge, Mohammed Jamshad, Haydn A Little, et al.
Molecular Pharmacology|December 25, 2015
A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal StructuresDenise Wootten, Christopher A Reynolds, Cassandra Koole, et al.
The Journal of Experimental Medicine|August 18, 2018
h<i>CALCRL</i> mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasiaDuncan I Mackie, Fuad Al Mutairi, Reema B Davis, et al.
Pageof 6

Showing results (41-50 of 53) with videos related to

Sort By:
Pageof 6
Cell Discovery|July 28, 2016
An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacologyJoseph J Gingell, John Simms, James Barwell, et al.
Biochimica Et Biophysica Acta. Biomembranes|December 31, 2019
Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptorsSarah J Routledge, John Simms, Ashley Clark, et al.
Frontiers in Endocrinology|January 31, 2022
The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor ActivationIan Winfield, Kerry Barkan, Sarah Routledge, et al.
Microbial Biotechnology|October 31, 2019
Preventive antibiotic treatment of calves: emergence of dysbiosis causing propagation of obese state-associated and mobile multidrug resistance-carrying bacteriaDorota A Dobrzanska, Matthew T F Lamaudière, Jessica Rollason, et al.
Molecular Pharmacology|June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screeningCassandra Koole, Denise Wootten, John Simms, et al.
Biochemical Pharmacology|July 15, 2017
Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to GsMichael J Woolley, Christopher A Reynolds, John Simms, et al.
Biochemistry|July 14, 2018
Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) ComplexJohn Simms, Romez Uddin, Thomas P Sakmar, et al.
Biochimica Et Biophysica Acta. Biomembranes|March 4, 2020
Ligand-induced conformational changes in a SMALP-encapsulated GPCRSarah J Routledge, Mohammed Jamshad, Haydn A Little, et al.
Molecular Pharmacology|December 25, 2015
A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal StructuresDenise Wootten, Christopher A Reynolds, Cassandra Koole, et al.
The Journal of Experimental Medicine|August 18, 2018
h<i>CALCRL</i> mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasiaDuncan I Mackie, Fuad Al Mutairi, Reema B Davis, et al.
Pageof 6