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Nature Structural Biology|May 15, 2002
Structural basis for the selective activation of Rho GTPases by Dbl exchange factorsJason T Snyder, David K Worthylake, Kent L Rossman, et al.
Biochemistry|October 8, 2020
A High-Throughput Assay to Identify Allosteric Inhibitors of the PLC-γ Isozymes Operating at MembranesWeigang Huang, Adam J Carr, Nicole Hajicek, et al.
The Journal of Biological Chemistry|December 22, 2017
A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymesWeigang Huang, Xiaoyang Wang, Stuart Endo-Streeter, et al.
Current Biology : CB|February 23, 2005
A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFsMingjian Lu, Jason M Kinchen, Kent L Rossman, et al.
The Journal of Biological Chemistry|October 16, 2016
Potent and Selective Peptide-based Inhibition of the G Protein GαqThomas H Charpentier, Gary L Waldo, Emily G Lowery-Gionta, et al.
The Journal of Biological Chemistry|March 6, 2007
Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motifMarielle E Yohe, Kent L Rossman, Olivia S Gardner, et al.
The Journal of Biological Chemistry|January 27, 2011
Direct activation of human phospholipase C by its well known inhibitor u73122Ryan R Klein, David M Bourdon, Chester L Costales, et al.
Elife|June 16, 2022
Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranesEdhriz Siraliev-Perez, Jordan T B Stariha, Reece M Hoffmann, et al.
The Journal of Biological Chemistry|February 27, 2025
A high-throughput assay platform to discover small molecule activators of the phospholipase PLC-γ2 to treat Alzheimer's diseaseAdam J Carr, Nicole Hajicek, Andy P Tsai, et al.
Biochimica Et Biophysica Acta|April 5, 2003
Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signalingWendy M Pruitt, Antoine E Karnoub, A Corinne Rakauskas, et al.
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