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Journal of Natural Products|September 20, 2008
Total synthesis and biological evaluation of the marine bromopyrrole alkaloid dispyrin: elucidation of discrete molecular targets with therapeutic potentialJ Phillip Kennedy, John T Brogan, Craig W Lindsley
ACS Chemical Neuroscience|September 29, 2012
Total synthesis and biological evaluation of phidianidines A and B uncovers unique pharmacological profiles at CNS targetsJohn T Brogan, Sydney L Stoops, Craig W Lindsley
Biochemistry|February 24, 2011
"Molecular switches" on mGluR allosteric ligands that modulate modes of pharmacologyMichael R Wood, Corey R Hopkins, John T Brogan, et al.
ACS Chemical Neuroscience|January 17, 2012
Total Synthesis (+)-7-Bromotrypargine and Unnatural Analogs: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic RelevanceJohn T Brogan, Sydney L Stoops, Brenda C Crews, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2015
Optimization of a small molecule probe that restores e-cadherin expressionJohn T Brogan, Sydney L Stoops, Suzanne Brady, et al.
Bioorganic & Medicinal Chemistry Letters|September 23, 2008
Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moietiesThomas M Bridges, Ashley E Brady, J Phillip Kennedy, et al.
ACS Chemical Biology|August 20, 2014
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenicsHyekyung P Cho, Pedro M Garcia-Barrantes, John T Brogan, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|January 21, 2014
Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100Nellie E Byun, Michael Grannan, Michael Bubser, et al.
ACS Chemical Neuroscience|February 28, 2012
The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson's DiseaseZixiu Xiang, Analisa D Thompson, John T Brogan, et al.
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