Showing results (1-10 of 32) with videos related to

Sort By:
Pageof 4
Journal of Biomolecular Screening|February 15, 2014
Overview of Recent Progress in Protein-Expression Technologies for Small-Molecule ScreeningJohn W Cuozzo, Holly H Soutter
The Journal of Biological Chemistry|October 7, 2004
Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activityBrenda S Luciano, Sang Hsu, Padma L Channavajhala, et al.
The Journal of Biological Chemistry|September 17, 2003
Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signalingPadma L Channavajhala, Leeying Wu, John W Cuozzo, et al.
Scientific Reports|June 11, 2015
Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member LibraryAlexander Litovchick, Christoph E Dumelin, Sevan Habeshian, et al.
Chembiochem : a European Journal of Chemical Biology|January 6, 2017
Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical LibraryJohn W Cuozzo, Paolo A Centrella, Diana Gikunju, et al.
Journal of Medicinal Chemistry|June 26, 2020
Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded ChemistryJohn W Cuozzo, Matthew A Clark, Anthony D Keefe, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2006
Inhibition of Tpl2 kinase and TNFalpha production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritisYonghan Hu, Neal Green, Lori K Gavrin, et al.
Bioorganic & Medicinal Chemistry|March 6, 2014
Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonistsChristopher S Kollmann, Xiaopeng Bai, Ching-Hsuan Tsai, et al.
Bioorganic & Medicinal Chemistry Letters|September 17, 2005
Inhibition of Tpl2 kinase and TNF-alpha production with 1,7-naphthyridine-3-carbonitriles: synthesis and structure-activity relationshipsLori Krim Gavrin, Neal Green, Yonghan Hu, et al.
ACS Medicinal Chemistry Letters|August 20, 2015
Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT)Yun Ding, Heather O'Keefe, Jennifer L DeLorey, et al.
Pageof 4