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Journal of Medicinal Chemistry|April 11, 2013
Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3Jeremy S Disch, Ghotas Evindar, Cynthia H Chiu, et al.Journal of Medicinal Chemistry|June 12, 2020
Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit FindingKevin McCloskey, Eric A Sigel, Steven Kearnes, et al.Proceedings of the National Academy of Sciences of the United States of America|November 20, 2016
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technologyHolly H Soutter, Paolo Centrella, Matthew A Clark, et al.Journal of Medicinal Chemistry|August 25, 2007
Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitrilesNeal Green, Yonghan Hu, Kristin Janz, et al.ACS Medicinal Chemistry Letters|April 16, 2021
Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 InhibitorsJohan J N Veerman, Yorik B Bruseker, Eddy Damen, et al.Journal of Medicinal Chemistry|May 6, 2021
Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library ScreeningEsther C Y Lee, Andrew J McRiner, Katy E Georgiadis, et al.Bioorganic & Medicinal Chemistry|June 6, 2021
Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistryJohn P Guilinger, Archna Archna, Martin Augustin, et al.ACS Medicinal Chemistry Letters|May 26, 2015
Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)Hongfang Yang, Patricia F Medeiros, Kaushik Raha, et al.SLAS Discovery : Advancing Life Sciences R & D|January 10, 2018
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the TargetDean G Brown, Giles A Brown, Paolo Centrella, et al.Journal of Medicinal Chemistry|November 23, 2023
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine LearningShabbir Ahmad, Jin Xu, Jianwen A Feng, et al.Pageof 4