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Plos One|October 22, 2014
The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormoneKim Nuytens, Krizia Tuand, Quili Fu, et al.
Oncogene|March 7, 2020
The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancerZongsheng He, Lieven Thorrez, Geraldine Siegfried, et al.
Scientific Reports|September 28, 2016
The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformersSven O Dahms, John W M Creemers, Yvonne Schaub, et al.
Molecular Metabolism|November 14, 2022
Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed miceIlaria Coppola, Bas Brouwers, Leanne Walker, et al.
Biochimica Et Biophysica Acta. Reviews on Cancer|May 29, 2026
Furin-like enzyme dependency in KRAS-mutant colorectal cancer as a target for personalized treatment strategiesGeraldine Siegfried, Yiyang Liu, Zongcheng He, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 27, 2012
Drosophila rugose is a functional homolog of mammalian Neurobeachin and affects synaptic architecture, brain morphology, and associative learningKarolien Volders, Sabrina Scholz, Jan R Slabbaert, et al.
Molecular Metabolism|March 9, 2017
Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolismDennis Löffler, Susanne Behrendt, John W M Creemers, et al.
The Journal of Clinical Endocrinology and Metabolism|June 28, 2007
Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3I Sadaf Farooqi, Karolien Volders, Richard Stanhope, et al.
Journal of the American Heart Association|April 23, 2018
Prodomain of Furin Promotes Phospholipid Transfer Protein Proteasomal Degradation in HepatocytesYang Yu, Xia Lei, Hui Jiang, et al.
Iscience|October 24, 2022
The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune toleranceZhanfeng Liang, Zhaoqi Zhang, Qian Zhang, et al.
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