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John W Nichols

Showing results (1-10 of 55) with videos related to

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Environmental Toxicology and Chemistry|October 25, 2022
Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of Blood-Water Partitioning and Chemical Volume of DistributionLeslie J Saunders, John W Nichols
Toxicological Sciences : an Official Journal of the Society of Toxicology|December 6, 2003
A physiologically based toxicokinetic model for dietary uptake of hydrophobic organic compounds by fish: II. simulation of chronic exposure scenariosJohn W Nichols, Patrick N Fitzsimmons, Frank W Whiteman
Applied in Vitro Toxicology|June 11, 2019
Measurement of kinetic parameters for biotransformation of polycyclic aromatic hydrocarbons by trout liver S9 fractions: Implications for bioaccumulation assessmentJohn W Nichols, Melanie A Ladd, Patrick N Fitzsimmons
Aquatic Toxicology (Amsterdam, Netherlands)|October 20, 2009
Optimization of an isolated perfused rainbow trout liver model: Clearance studies with 7-ethoxycoumarinJohn W Nichols, Alex D Hoffman, Patrick N Fitzsimmons
Aquatic Toxicology (Amsterdam, Netherlands)|March 4, 2006
In vitro-in vivo extrapolation of quantitative hepatic biotransformation data for fish. I. A review of methods, and strategies for incorporating intrinsic clearance estimates into chemical kinetic modelsJohn W Nichols, Irvin R Schultz, Patrick N Fitzsimmons
Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP|March 16, 2007
A compilation of in vitro rate and affinity values for xenobiotic biotransformation in fish, measured under physiological conditionsPatrick N Fitzsimmons, Gregory J Lien, John W Nichols
Environmental Toxicology and Chemistry|June 19, 2007
In vitro-in vivo extrapolation of quantitative hepatic biotransformation data for fish. II. Modeled effects on chemical bioaccumulationJohn W Nichols, Patrick N Fitzsimmons, Lawrence P Burkhard
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 8, 2016
Optimization of a UDP-glucuronosyltransferase assay for trout liver S9 fractions: activity enhancement by alamethicin, a pore-forming peptideMelanie A Ladd, Patrick N Fitzsimmons, John W Nichols
Environmental Toxicology and Chemistry|April 4, 2023
In Vitro-In Vivo Extrapolation of Hepatic Biotransformation Data for Fish. III. An In-depth Case Study with PyreneJohn W Nichols, Patrick N Fitzsimmons, Alex D Hoffman, et al.
Environmental Toxicology and Chemistry|August 4, 2016
Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fishKellie A Fay, Patrick N Fitzsimmons, Alex D Hoffman, et al.
Pageof 6

Showing results (1-10 of 55) with videos related to

Sort By:
Pageof 6
Environmental Toxicology and Chemistry|October 25, 2022
Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of Blood-Water Partitioning and Chemical Volume of DistributionLeslie J Saunders, John W Nichols
Toxicological Sciences : an Official Journal of the Society of Toxicology|December 6, 2003
A physiologically based toxicokinetic model for dietary uptake of hydrophobic organic compounds by fish: II. simulation of chronic exposure scenariosJohn W Nichols, Patrick N Fitzsimmons, Frank W Whiteman
Applied in Vitro Toxicology|June 11, 2019
Measurement of kinetic parameters for biotransformation of polycyclic aromatic hydrocarbons by trout liver S9 fractions: Implications for bioaccumulation assessmentJohn W Nichols, Melanie A Ladd, Patrick N Fitzsimmons
Aquatic Toxicology (Amsterdam, Netherlands)|October 20, 2009
Optimization of an isolated perfused rainbow trout liver model: Clearance studies with 7-ethoxycoumarinJohn W Nichols, Alex D Hoffman, Patrick N Fitzsimmons
Aquatic Toxicology (Amsterdam, Netherlands)|March 4, 2006
In vitro-in vivo extrapolation of quantitative hepatic biotransformation data for fish. I. A review of methods, and strategies for incorporating intrinsic clearance estimates into chemical kinetic modelsJohn W Nichols, Irvin R Schultz, Patrick N Fitzsimmons
Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP|March 16, 2007
A compilation of in vitro rate and affinity values for xenobiotic biotransformation in fish, measured under physiological conditionsPatrick N Fitzsimmons, Gregory J Lien, John W Nichols
Environmental Toxicology and Chemistry|June 19, 2007
In vitro-in vivo extrapolation of quantitative hepatic biotransformation data for fish. II. Modeled effects on chemical bioaccumulationJohn W Nichols, Patrick N Fitzsimmons, Lawrence P Burkhard
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 8, 2016
Optimization of a UDP-glucuronosyltransferase assay for trout liver S9 fractions: activity enhancement by alamethicin, a pore-forming peptideMelanie A Ladd, Patrick N Fitzsimmons, John W Nichols
Environmental Toxicology and Chemistry|April 4, 2023
In Vitro-In Vivo Extrapolation of Hepatic Biotransformation Data for Fish. III. An In-depth Case Study with PyreneJohn W Nichols, Patrick N Fitzsimmons, Alex D Hoffman, et al.
Environmental Toxicology and Chemistry|August 4, 2016
Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fishKellie A Fay, Patrick N Fitzsimmons, Alex D Hoffman, et al.
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