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Biochemistry|August 21, 2015
Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone MethyltransferaseDavid S Rogawski, Juliano Ndoj, Hyo Je Cho, et al.European Journal of Medicinal Chemistry|September 4, 2020
Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interactionPaulina Fortuna, Brian M Linhares, Trupta Purohit, et al.Journal of Medicinal Chemistry|August 20, 2015
Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand ComplexesJonathan Pollock, Dmitry Borkin, George Lund, et al.Biochemistry|March 15, 2006
The binding of the PDZ tandem of syntenin to target proteinsJolanta Grembecka, Tomasz Cierpicki, Yancho Devedjiev, et al.Journal of Molecular Biology|October 25, 2006
A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulationZhe Li, Steven M Lukasik, Yizhou Liu, et al.Nature Communications|November 17, 2022
Increased slow dynamics defines ligandability of BTB domainsVladlena Kharchenko, Brian M Linhares, Megan Borregard, et al.Structure (London, England : 1993)|August 1, 2023
MRG15 activates histone methyltransferase activity of ASH1L by recruiting it to the nucleosomesSamah Al-Harthi, Hao Li, Alyssa Winkler, et al.Experimental Hematology|October 14, 2018
Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemiaYufei Chen, Kenneth L Jones, Konstantinos Anastassiadis, et al.Molecular Cancer Therapeutics|November 17, 2017
Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular CarcinomaKatarzyna Kempinska, Bhavna Malik, Dmitry Borkin, et al.ACS Chemical Biology|August 4, 2018
GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding ModeHyo Je Cho, Hao Li, Brian M Linhares, et al.Pageof 8