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Leukemia|June 18, 2024
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocationsHongzhi Miao, Dong Chen, James Ropa, et al.Chemistry & Biology|September 27, 2005
Structure-based discovery of a boronic acid bioisostere of combretastatin A-4Yali Kong, Jolanta Grembecka, Michael C Edler, et al.Leukemia|January 26, 2019
CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complexLuisa Schmidt, Elizabeth Heyes, Lisa Scheiblecker, et al.Blood|September 1, 2012
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemiaAibin Shi, Marcelo J Murai, Shihan He, et al.Cancer Research Communications|July 26, 2023
Clinically Defined Mutations in <i>MEN1</i> Alter Its Tumor-suppressive Function Through Increased Menin TurnoverSuzann Duan, Sulaiman Sheriff, Uloma B Elvis-Offiah, et al.Nature Structural & Molecular Biology|December 17, 2009
Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemiaTomasz Cierpicki, Laurie E Risner, Jolanta Grembecka, et al.Blood|October 12, 2014
The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIVMarcelo J Murai, Jonathan Pollock, Shihan He, et al.Journal of Medicinal Chemistry|January 2, 2025
Development of PRC1 Inhibitors Employing Fragment-Based Approach and NMR-Guided OptimizationYiwu Yao, Miranda L Simes, Weijiang Ying, et al.Journal of Medicinal Chemistry|October 27, 2007
Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compoundsTina S Skinner-Adams, Jonathan Lowther, Franka Teuscher, et al.Nature Communications|November 10, 2016
BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerizationFelicia Gray, Hyo Je Cho, Shirish Shukla, et al.Pageof 8