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Leukemia & Lymphoma|December 19, 2017
A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cellsZaw Min Oo, Anuradha Illendula, Jolanta Grembecka, et al.
Journal of Leukocyte Biology|June 11, 2015
Epigenetic regulation of IL-12-dependent T cell proliferationMatthew Schaller, Toshihiro Ito, Ronald M Allen, et al.
Nature Chemical Biology|January 31, 2012
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemiaJolanta Grembecka, Shihan He, Aibin Shi, et al.
Journal of Medicinal Chemistry|December 16, 2024
Structure-Based Development of Novel Spiro-Piperidine ASH1L InhibitorsGuang Huang, Rhiannon Stevens, Devon G Hucek, et al.
Science (New York, N.Y.)|February 14, 2015
Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in miceAnuradha Illendula, John A Pulikkan, Hongliang Zong, et al.
Oncotarget|November 27, 2016
Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and meninLaurie K Svoboda, Natashay Bailey, Raelene A Van Noord, et al.
The Journal of Biological Chemistry|November 17, 2006
Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug developmentColin M Stack, Jonathan Lowther, Eithne Cunningham, et al.
Trends in Biochemical Sciences|October 3, 2009
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarialsTina S Skinner-Adams, Colin M Stack, Katharine R Trenholme, et al.
Plos One|November 9, 2013
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypesNicolai A Kittan, Ronald M Allen, Abhay Dhaliwal, et al.
Genome Biology|February 5, 2025
SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylationRyan T Wagner, Ryan A Hlady, Xiaoyu Pan, et al.
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