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Cancer Discovery|December 1, 2022
Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid LeukemiaXue Qing David Wang, Dandan Fan, Qinyu Han, et al.
Journal of Medicinal Chemistry|November 26, 2025
Discovery and Development of a Small-Molecule Inhibitor Targeting the GAS41 YEATS Domain in Nonsmall Cell Lung CancerDymytrii Listunov, Alyssa Winkler, Joshua Ray, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 6, 2010
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidasesSheena McGowan, Christine A Oellig, Woldeamanuel A Birru, et al.
Molecular Cancer Research : MCR|March 20, 2021
EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing SarcomaJennifer A Jiménez, April A Apfelbaum, Allegra G Hawkins, et al.
Chemistry & Biology|October 27, 2007
Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbetaMichael J Gorczynski, Jolanta Grembecka, Yunpeng Zhou, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 7, 2009
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidaseSheena McGowan, Corrine J Porter, Jonathan Lowther, et al.
The Journal of Pathology|April 20, 2018
Menin regulates the serine biosynthetic pathway in Ewing sarcomaLaurie K Svoboda, Selina Shiqing K Teh, Sudha Sud, et al.
Gastroenterology|September 2, 2017
Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial CellsSinju Sundaresan, Cameron A Meininger, Anthony J Kang, et al.
Nature Chemical Biology|September 2, 2020
Covalent inhibition of NSD1 histone methyltransferaseHuang Huang, Christina A Howard, Sergei Zari, et al.
Cancer Cell|March 31, 2015
Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivoDmitry Borkin, Shihan He, Hongzhi Miao, et al.
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