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Structure (London, England : 1993)|November 15, 2022
Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulationJ Ryan Feathers, Erica K Richael, Kayla A Simanek, et al.
Nature Communications|December 2, 2023
Quorum-sensing synthase mutations re-calibrate autoinducer concentrations in clinical isolates of Pseudomonas aeruginosa to enhance pathogenesisKayla A Simanek, Megan L Schumacher, Caleb P Mallery, et al.
Microbiology Spectrum|January 12, 2022
The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosaKayla A Simanek, Isabelle R Taylor, Erica K Richael, et al.
ACS Chemical Biology|April 1, 2021
Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor ProductionIsabelle R Taylor, Jon E Paczkowski, Philip D Jeffrey, et al.
The Journal of Biological Chemistry|January 23, 2020
Mechanism underlying autoinducer recognition in the Vibrio cholerae DPO-VqmA quorum-sensing pathwayXiuliang Huang, Olivia P Duddy, Justin E Silpe, et al.
Biorxiv : the Preprint Server for Biology|February 26, 2024
Ligand binding determines proteolytic stability of Vibrio LuxR/HapR quorum sensing transcription factorsTanmaya A Rasal, Caleb P Mallery, Matthew W Brockley, et al.
Biorxiv : the Preprint Server for Biology|June 4, 2026
The conserved coordination of acyl-homoserine lactone and PqsE signaling defines the RhlR-dependent quorum-sensing network in Pseudomonas aeruginosa clinical isolatesElizabeth G Knorr, Elizabeth A Key, Megan L Schumacher, et al.
Plos Genetics|December 8, 2023
Promoter selectivity of the RhlR quorum-sensing transcription factor receptor in Pseudomonas aeruginosa is coordinated by distinct and overlapping dependencies on C4-homoserine lactone and PqsENicholas R Keegan, Nathalie J Colón Torres, Anne M Stringer, et al.
The Journal of Biological Chemistry|January 26, 2017
Flavonoids Suppress Pseudomonas aeruginosa Virulence through Allosteric Inhibition of Quorum-sensing ReceptorsJon E Paczkowski, Sampriti Mukherjee, Amelia R McCready, et al.
ACS Chemical Biology|February 15, 2019
An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing ReceptorJon E Paczkowski, Amelia R McCready, Jian-Ping Cong, et al.
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