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Circulation. Heart Failure|August 13, 2011
Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failureGuido Boerrigter, Michael W Lark, Erin J Whalen, et al.
Neuropharmacology|December 17, 2018
Delta opioid receptor agonists are effective for multiple types of headache disordersLaura S Moye, Alycia F Tipton, Isaac Dripps, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 16, 2008
Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptorsArun K Shukla, Jonathan D Violin, Erin J Whalen, et al.
The Journal of Biological Chemistry|December 19, 2007
beta-arrestin-biased agonism at the beta2-adrenergic receptorMatthew T Drake, Jonathan D Violin, Erin J Whalen, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 13, 2008
Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivationIl-Man Kim, Douglas G Tilley, Juhsien Chen, et al.
Journal of Clinical Pharmacology|October 15, 2013
First clinical experience with TRV130: pharmacokinetics and pharmacodynamics in healthy volunteersDavid G Soergel, Ruth Ann Subach, Brian Sadler, et al.
Molecular Pharmacology|May 26, 2011
Quantifying ligand bias at seven-transmembrane receptorsSudarshan Rajagopal, Seungkirl Ahn, David H Rominger, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 31, 2010
Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performanceJonathan D Violin, Scott M DeWire, Dennis Yamashita, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 11, 2007
A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signalingJames W Wisler, Scott M DeWire, Erin J Whalen, et al.
American Journal of Physiology. Heart and Circulatory Physiology|July 23, 2013
The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calciumMichelle M Monasky, Domenico M Taglieri, Marcus Henze, et al.
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