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Jonathan M Large

Showing results (11-20 of 24) with videos related to

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Bioorganic & Medicinal Chemistry Letters|September 9, 2008
Synthesis and in vitro evaluation of imidazopyridazines as novel inhibitors of the malarial kinase PfPK7Nathalie Bouloc, Jonathan M Large, Ela Smiljanic, et al.
Chembiochem : a European Journal of Chemical Biology|December 4, 2018
Developing an Antibody-Drug Conjugate Approach to Selective Inhibition of an Extracellular ProteinElizabeth A Love, Afrah Sattikar, Hannah Cook, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV‑2 NSP14Elliott B Smyth, João P Pisco, Kristian Birchall, et al.
Biochemical and Biophysical Research Communications|September 9, 2017
Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3Paul D Wright, Emma L Veale, David McCoull, et al.
Biochemical and Biophysical Research Communications|October 1, 2019
Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2Paul D Wright, David McCoull, Yvonne Walsh, et al.
Bioorganic & Medicinal Chemistry Letters|September 17, 2013
Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analoguesJonathan M Large, Simon A Osborne, Ela Smiljanic-Hurley, et al.
Bioorganic & Medicinal Chemistry Letters|September 14, 2010
Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cellsNathalie Bouloc, Jonathan M Large, Magda Kosmopoulou, et al.
Bioorganic & Medicinal Chemistry|January 11, 2011
Preparation and evaluation of trisubstituted pyrimidines as phosphatidylinositol 3-kinase inhibitors. 3-Hydroxyphenol analogues and bioisosteric replacementsJonathan M Large, Jane E Torr, Florence I Raynaud, et al.
Bioorganic & Medicinal Chemistry Letters|April 11, 2013
Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)Timothy M Chapman, Simon A Osborne, Nathalie Bouloc, et al.
Bioorganic & Medicinal Chemistry Letters|September 4, 2018
Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG)Denise J Tsagris, Kristian Birchall, Nathalie Bouloc, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

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Bioorganic & Medicinal Chemistry Letters|September 9, 2008
Synthesis and in vitro evaluation of imidazopyridazines as novel inhibitors of the malarial kinase PfPK7Nathalie Bouloc, Jonathan M Large, Ela Smiljanic, et al.
Chembiochem : a European Journal of Chemical Biology|December 4, 2018
Developing an Antibody-Drug Conjugate Approach to Selective Inhibition of an Extracellular ProteinElizabeth A Love, Afrah Sattikar, Hannah Cook, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV‑2 NSP14Elliott B Smyth, João P Pisco, Kristian Birchall, et al.
Biochemical and Biophysical Research Communications|September 9, 2017
Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3Paul D Wright, Emma L Veale, David McCoull, et al.
Biochemical and Biophysical Research Communications|October 1, 2019
Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2Paul D Wright, David McCoull, Yvonne Walsh, et al.
Bioorganic & Medicinal Chemistry Letters|September 17, 2013
Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analoguesJonathan M Large, Simon A Osborne, Ela Smiljanic-Hurley, et al.
Bioorganic & Medicinal Chemistry Letters|September 14, 2010
Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cellsNathalie Bouloc, Jonathan M Large, Magda Kosmopoulou, et al.
Bioorganic & Medicinal Chemistry|January 11, 2011
Preparation and evaluation of trisubstituted pyrimidines as phosphatidylinositol 3-kinase inhibitors. 3-Hydroxyphenol analogues and bioisosteric replacementsJonathan M Large, Jane E Torr, Florence I Raynaud, et al.
Bioorganic & Medicinal Chemistry Letters|April 11, 2013
Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1)Timothy M Chapman, Simon A Osborne, Nathalie Bouloc, et al.
Bioorganic & Medicinal Chemistry Letters|September 4, 2018
Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG)Denise J Tsagris, Kristian Birchall, Nathalie Bouloc, et al.
Pageof 3