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International Journal of Toxicology
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March 5, 2022
Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison
Mylène Pouliot, Jeanine Bussiere, Aldo Coppi, et al.
Toxicologic Pathology
|
March 4, 2020
Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs
Paula Katavolos, Gary Cain, Cindy Farman, et al.
Lab on a Chip
|
January 20, 2021
Cardiovascular microphysiological systems (CVMPS) for safety studies - a pharma perspective
Amy Pointon, Jonathan Maher, Myrtle Davis, et al.
Toxicology and Applied Pharmacology
|
November 18, 2017
Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition
Steven Cepa, David Potter, Lisa Wong, et al.
Toxicology and Applied Pharmacology
|
July 15, 2023
Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats
Jonathan Maher, Nicola Stagg, Gary Cain, et al.
Journal of Leukocyte Biology
|
January 28, 2020
RIP1 kinase activity is critical for skin inflammation but not for viral propagation
Joshua D Webster, Youngsu C Kwon, Summer Park, et al.
Clinical Pharmacology and Therapeutics
|
August 24, 2018
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective
J Gerry Kenna, Kunal S Taskar, Christina Battista, et al.
ACS Medicinal Chemistry Letters
|
March 19, 2020
Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity
Naomi S Rajapaksa, Alberto Gobbi, Joy Drobnick, et al.
Journal of Medicinal Chemistry
|
May 15, 2019
Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors
Marian C Bryan, Joy Drobnick, Alberto Gobbi, et al.
Journal of Medicinal Chemistry
|
October 30, 2025
Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases
Snahel Patel, Huifen Chen, Eugene Varfolomeev, et al.
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of 3
Search research articles
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Showing results (11-20 of 25) with videos related to
Sort By:
Page
of 3
International Journal of Toxicology
|
March 5, 2022
Polysorbate 80-Induced Anaphylactoid Reaction and the Effects on Cardiovascular Function: Dose Threshold and Species Comparison
Mylène Pouliot, Jeanine Bussiere, Aldo Coppi, et al.
Toxicologic Pathology
|
March 4, 2020
Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs
Paula Katavolos, Gary Cain, Cindy Farman, et al.
Lab on a Chip
|
January 20, 2021
Cardiovascular microphysiological systems (CVMPS) for safety studies - a pharma perspective
Amy Pointon, Jonathan Maher, Myrtle Davis, et al.
Toxicology and Applied Pharmacology
|
November 18, 2017
Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition
Steven Cepa, David Potter, Lisa Wong, et al.
Toxicology and Applied Pharmacology
|
July 15, 2023
Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats
Jonathan Maher, Nicola Stagg, Gary Cain, et al.
Journal of Leukocyte Biology
|
January 28, 2020
RIP1 kinase activity is critical for skin inflammation but not for viral propagation
Joshua D Webster, Youngsu C Kwon, Summer Park, et al.
Clinical Pharmacology and Therapeutics
|
August 24, 2018
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective
J Gerry Kenna, Kunal S Taskar, Christina Battista, et al.
ACS Medicinal Chemistry Letters
|
March 19, 2020
Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity
Naomi S Rajapaksa, Alberto Gobbi, Joy Drobnick, et al.
Journal of Medicinal Chemistry
|
May 15, 2019
Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors
Marian C Bryan, Joy Drobnick, Alberto Gobbi, et al.
Journal of Medicinal Chemistry
|
October 30, 2025
Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases
Snahel Patel, Huifen Chen, Eugene Varfolomeev, et al.
Page
of 3