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Angewandte Chemie (International Ed. in English)
|
August 31, 2017
Lysine-Targeting Covalent Inhibitors
Jonathan Pettinger, Keith Jones, Matthew D Cheeseman
Journal of Medicinal Chemistry
|
November 15, 2019
Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72
Jonathan Pettinger, Michael Carter, Keith Jones, et al.
Angewandte Chemie (International Ed. in English)
|
February 23, 2017
An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56
Jonathan Pettinger, Yann-Vaï Le Bihan, Marcella Widya, et al.
Chemical Science
|
May 14, 2025
Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination
Katherine A McPhie, Diego Esposito, Jonathan Pettinger, et al.
The Journal of Organic Chemistry
|
May 23, 2024
One-Pot Oxidative Amidation of Aldehydes via the Generation of Nitrile Imine Intermediates
Martyn C Henry, Laura Minty, Alexander C W Kwok, et al.
Communications Chemistry
|
January 14, 2025
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation
Aini Vuorinen, Cassandra R Kennedy, Katherine A McPhie, et al.
ACS Chemical Biology
|
January 17, 2023
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, et al.
RSC Chemical Biology
|
November 6, 2025
Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2
Cassandra R Kennedy, Katherine A McPhie, Aini Vuorinen, et al.
Angewandte Chemie (International Ed. in English)
|
December 4, 2024
Expedited SARS-CoV-2 Main Protease Inhibitor Discovery through Modular 'Direct-to-Biology' Screening
Harry Wilders, George Biggs, Sam M Rowe, et al.
Nature Communications
|
January 2, 2025
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics
George S Biggs, Emma E Cawood, Aini Vuorinen, et al.
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Search research articles
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Showing results (1-10 of 12) with videos related to
Sort By:
Page
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Angewandte Chemie (International Ed. in English)
|
August 31, 2017
Lysine-Targeting Covalent Inhibitors
Jonathan Pettinger, Keith Jones, Matthew D Cheeseman
Journal of Medicinal Chemistry
|
November 15, 2019
Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72
Jonathan Pettinger, Michael Carter, Keith Jones, et al.
Angewandte Chemie (International Ed. in English)
|
February 23, 2017
An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56
Jonathan Pettinger, Yann-Vaï Le Bihan, Marcella Widya, et al.
Chemical Science
|
May 14, 2025
Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination
Katherine A McPhie, Diego Esposito, Jonathan Pettinger, et al.
The Journal of Organic Chemistry
|
May 23, 2024
One-Pot Oxidative Amidation of Aldehydes via the Generation of Nitrile Imine Intermediates
Martyn C Henry, Laura Minty, Alexander C W Kwok, et al.
Communications Chemistry
|
January 14, 2025
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation
Aini Vuorinen, Cassandra R Kennedy, Katherine A McPhie, et al.
ACS Chemical Biology
|
January 17, 2023
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome
Katharine E Gilbert, Aini Vuorinen, Arron Aatkar, et al.
RSC Chemical Biology
|
November 6, 2025
Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2
Cassandra R Kennedy, Katherine A McPhie, Aini Vuorinen, et al.
Angewandte Chemie (International Ed. in English)
|
December 4, 2024
Expedited SARS-CoV-2 Main Protease Inhibitor Discovery through Modular 'Direct-to-Biology' Screening
Harry Wilders, George Biggs, Sam M Rowe, et al.
Nature Communications
|
January 2, 2025
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics
George S Biggs, Emma E Cawood, Aini Vuorinen, et al.
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of 2