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Biorxiv : the Preprint Server for Biology|October 24, 2023
Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial CalciumAnagha Inguva Sheth, Krysta Engel, Hunter Tolison, et al.
Leukemia|February 13, 2022
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cellsBoaz Nachmias, Dilshad H Khan, Veronique Voisin, et al.
Nature Communications|November 2, 2021
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitorsTeklab Gebregiworgis, Yoshihito Kano, Jonathan St-Germain, et al.
Haematologica|April 6, 2023
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicityCristiana O'Brien, Tianyi Ling, Jacob M Berman, et al.
Cancer Discovery|May 24, 2024
Targeting Acute Myeloid Leukemia Stem Cells through Perturbation of Mitochondrial CalciumAnagha Inguva Sheth, Mark J Althoff, Hunter Tolison, et al.
Science Translational Medicine|September 25, 2024
Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse modelsVincent Rondeau, Jacob M Berman, Tianyi Ling, et al.
The Journal of Clinical Investigation|February 2, 2021
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumorsParasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, et al.
Cancer Research|May 14, 2025
SMARCA4 loss increases RNA Polymerase II pausing and elevates R-loops to inhibit BRCA1-mediated repair in ovarian cancerXianbing Zhu, Zheng Fu, Giulio Aceto, et al.
Biorxiv : the Preprint Server for Biology|November 14, 2023
Recruitment of FBXO22 for Targeted Degradation of NSD2David Y Nie, John R Tabor, Jianping Li, et al.
Blood|November 14, 2025
Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulationTianyi Ling, Cristiana O'Brien, Jonathan St-Germain, et al.
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