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Mabs|July 2, 2019
Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRPαJanet Sim, Jonathan T Sockolosky, Emma Sangalang, et al.Journal of Hematology & Oncology|December 1, 2020
Targeting the myeloid checkpoint receptor SIRPα potentiates innate and adaptive immune responses to promote anti-tumor activityTracy C Kuo, Amy Chen, Ons Harrabi, et al.Nature Communications|January 20, 2024
i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonistsMatthew G Romei, Brandon Leonard, Zachary B Katz, et al.Science (New York, N.Y.)|March 3, 2018
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexesJonathan T Sockolosky, Eleonora Trotta, Giulia Parisi, et al.Cell|March 12, 2017
Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit SignalingChia Chi M Ho, Akanksha Chhabra, Philipp Starkl, et al.Journal for Immunotherapy of Cancer|July 15, 2025
Engineered IL-18 variants with half-life extension and improved stability for cancer immunotherapyTravis W Bainbridge, Lifen Wang, Marina Moskalenko, et al.Pageof 2