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ACS Medicinal Chemistry Letters
|
June 24, 2015
Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4
Jongwon Lim, Michael D Altman, James Baker, et al.
Molecular Cancer Research : MCR
|
April 23, 2014
Evaluating TBK1 as a therapeutic target in cancers with activated IRF3
Asli Muvaffak, Qi Pan, Haiyan Yan, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2021
Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds
Brandon A Vara, Samuel M Levi, Abdelghani Achab, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2020
Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1)
Catherine White, Meredeth A McGowan, Hua Zhou, et al.
Journal of Medicinal Chemistry
|
February 12, 2026
Discovery and In Vivo Evaluation of Aryl Ether YAP1/TEAD Inhibitors for the Treatment of Hippo-Driven Malignancies
Brandon A Vara, Jongwon Lim, Casey J Moure, et al.
Plos One
|
May 25, 2012
Efficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia vera
Manfred Kraus, Yuxun Wang, Dan Aleksandrowicz, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 15, 2017
Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation
Graham F Smith, Michael D Altman, Brian Andresen, et al.
Journal of Medicinal Chemistry
|
May 26, 2011
Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer
Jason D Katz, James P Jewell, David J Guerin, et al.
Journal of Medicinal Chemistry
|
March 23, 2021
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer
Ryan V Quiroz, Michael H Reutershan, Sebastian E Schneider, et al.
ACS Medicinal Chemistry Letters
|
March 19, 2021
Carbamate and <i>N</i>-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors
Derun Li, Yongqi Deng, Abdelghani Achab, et al.
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Search research articles
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Showing results (41-50 of 53) with videos related to
Sort By:
Page
of 6
ACS Medicinal Chemistry Letters
|
June 24, 2015
Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4
Jongwon Lim, Michael D Altman, James Baker, et al.
Molecular Cancer Research : MCR
|
April 23, 2014
Evaluating TBK1 as a therapeutic target in cancers with activated IRF3
Asli Muvaffak, Qi Pan, Haiyan Yan, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2021
Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds
Brandon A Vara, Samuel M Levi, Abdelghani Achab, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2020
Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1)
Catherine White, Meredeth A McGowan, Hua Zhou, et al.
Journal of Medicinal Chemistry
|
February 12, 2026
Discovery and In Vivo Evaluation of Aryl Ether YAP1/TEAD Inhibitors for the Treatment of Hippo-Driven Malignancies
Brandon A Vara, Jongwon Lim, Casey J Moure, et al.
Plos One
|
May 25, 2012
Efficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia vera
Manfred Kraus, Yuxun Wang, Dan Aleksandrowicz, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 15, 2017
Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation
Graham F Smith, Michael D Altman, Brian Andresen, et al.
Journal of Medicinal Chemistry
|
May 26, 2011
Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer
Jason D Katz, James P Jewell, David J Guerin, et al.
Journal of Medicinal Chemistry
|
March 23, 2021
The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer
Ryan V Quiroz, Michael H Reutershan, Sebastian E Schneider, et al.
ACS Medicinal Chemistry Letters
|
March 19, 2021
Carbamate and <i>N</i>-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors
Derun Li, Yongqi Deng, Abdelghani Achab, et al.
Page
of 6