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Proceedings of the National Academy of Sciences of the United States of America
|
May 3, 2006
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition
Hans-Guido Wendel, Elisa de Stanchina, Enriqué Cepero, et al.
Neoplasia (New York, N.Y.)
|
January 15, 2010
INCB16562, a JAK1/2 selective inhibitor, is efficacious against multiple myeloma cells and reverses the protective effects of cytokine and stromal cell support
Jun Li, Margaret Favata, Jennifer A Kelley, et al.
Molecular Cancer Therapeutics
|
February 4, 2010
Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors
Holly K Koblish, Michael J Hansbury, Kevin J Bowman, et al.
Molecular Cancer Therapeutics
|
January 14, 2009
Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo
Renate Burger, Steven Le Gouill, Yu-Tzu Tai, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
March 17, 2007
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer
Jordan S Fridman, Eian Caulder, Michael Hansbury, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 11, 2007
Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutations
David M Burns, Chunhong He, Yanlong Li, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
September 16, 2011
A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3
Xiangdong Liu, Qian Wang, Gengjie Yang, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 22, 2009
Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibition
David M Burns, Yun-Long Li, Eric Shi, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 6, 2009
Combined inhibition of Janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity
Phillip C C Liu, Eian Caulder, Jun Li, et al.
The Journal of Investigative Dermatology
|
June 17, 2011
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation
Jordan S Fridman, Peggy A Scherle, Robert Collins, et al.
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Search research articles
Search
Showing results (11-20 of 31) with videos related to
Sort By:
Page
of 4
Proceedings of the National Academy of Sciences of the United States of America
|
May 3, 2006
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition
Hans-Guido Wendel, Elisa de Stanchina, Enriqué Cepero, et al.
Neoplasia (New York, N.Y.)
|
January 15, 2010
INCB16562, a JAK1/2 selective inhibitor, is efficacious against multiple myeloma cells and reverses the protective effects of cytokine and stromal cell support
Jun Li, Margaret Favata, Jennifer A Kelley, et al.
Molecular Cancer Therapeutics
|
February 4, 2010
Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors
Holly K Koblish, Michael J Hansbury, Kevin J Bowman, et al.
Molecular Cancer Therapeutics
|
January 14, 2009
Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo
Renate Burger, Steven Le Gouill, Yu-Tzu Tai, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
March 17, 2007
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer
Jordan S Fridman, Eian Caulder, Michael Hansbury, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 11, 2007
Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutations
David M Burns, Chunhong He, Yanlong Li, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
September 16, 2011
A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3
Xiangdong Liu, Qian Wang, Gengjie Yang, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 22, 2009
Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibition
David M Burns, Yun-Long Li, Eric Shi, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 6, 2009
Combined inhibition of Janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity
Phillip C C Liu, Eian Caulder, Jun Li, et al.
The Journal of Investigative Dermatology
|
June 17, 2011
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation
Jordan S Fridman, Peggy A Scherle, Robert Collins, et al.
Page
of 4