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Biochemistry|November 26, 2003
The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundlePeng Zhai, Xiangyuan He, Jian Liu, et al.
Biochemistry|July 3, 2002
Specificity of memapsin 1 and its implications on the design of memapsin 2 (beta-secretase) inhibitor selectivityRobert T Turner, Jeffrey A Loy, Chan Nguyen, et al.
The EMBO Journal|October 1, 2004
Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5Guangyu Zhu, Peng Zhai, Xiangyuan He, et al.
Biochemistry|May 28, 2003
Crystal structure of the human GGA1 GAT domainGuangyu Zhu, Peng Zhai, Xiangyuan He, et al.
Applied Microbiology and Biotechnology|January 25, 2012
Inhibition of anthrax lethal factor: lability of hydroxamate as a chelating groupFeng Li, Irina Chvyrkova, Simon Terzyan, et al.
Bioorganic & Medicinal Chemistry Letters|August 7, 2012
Structure-based design, synthesis, and biological evaluation of dihydroquinazoline-derived potent β-secretase inhibitorsArun K Ghosh, Satyendra Pandey, Sudhakar Gangarajula, et al.
Bioorganic & Medicinal Chemistry Letters|December 8, 2004
Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase)Arun K Ghosh, Thippeswamy Devasamudram, Lin Hong, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|November 10, 2010
Beta-secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic miceWan-Pin Chang, Xiangping Huang, Deborah Downs, et al.
Journal of Medicinal Chemistry|September 8, 2012
Structure-based design of highly selective β-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structureArun K Ghosh, Kalapala Venkateswara Rao, Navnath D Yadav, et al.
Bioorganic & Medicinal Chemistry Letters|July 5, 2018
Design, synthesis, X-ray studies, and biological evaluation of novel BACE1 inhibitors with bicyclic isoxazoline carboxamides as the P3 ligandArun K Ghosh, Koena Ghosh, Margherita Brindisi, et al.
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