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Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|August 18, 2017
Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 ResultsEriene A Youssef, Elizabeth Berry-Kravis, Christian Czech, et al.Clinical Pharmacology and Therapeutics|December 9, 2024
Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled TrialTitia Q Ruijs, Catherine M K E de Cuba, Jules A A C Heuberger, et al.The Journal of Clinical Investigation|July 9, 2026
Neuromuscular junction failure in sarcopenia is linked to NaV1.4 loss and reversed by ClC-1 inhibitionW David Arnold, Jeanette Jeppesen Morgen, Pernille Bogetofte Thomasen, et al.Science Translational Medicine|March 20, 2024
The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravisMartin Skov, Titia Q Ruijs, Thomas S Grønnebæk, et al.Biological Psychiatry|January 5, 2017
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression PhenotypeNese Direk, Stephanie Williams, Jennifer A Smith, et al.Nature Genetics|April 28, 2018
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressionNaomi R Wray, Stephan Ripke, Manuel Mattheisen, et al.Pageof 3