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Nucleus (Austin, Tex.)|December 5, 2023
The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-BKamsi O Odinammadu, Khurts Shilagardi, Kelsey Tuminelli, et al.
Eukaryotic Cell|September 12, 2006
Saccharomyces cerevisiae a-factor mutants reveal residues critical for processing, activity, and exportGregory Huyer, Amy Kistler, Franklin J Nouvet, et al.
The Journal of Biological Chemistry|January 1, 2023
Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality controlWei Wang, Jian Lu, Wei-Chih Yang, et al.
JCI Insight|February 3, 2026
Stem cell-associated osteogenic deficiency causes craniofacial deformities with progeroid accumulation of prelamin AKai Li, Trunee Hsu, Hitoshi Uchida, et al.
Eukaryotic Cell|November 29, 2002
Localization, regulation, and substrate transport properties of Bpt1p, a Saccharomyces cerevisiae MRP-type ABC transporterKailash Gulshan Sharma, Deborah L Mason, Guosheng Liu, et al.
Biochemical and Biophysical Research Communications|July 22, 2008
HIV-protease inhibitors block the enzymatic activity of purified Ste24pSarah E Hudon, Catherine Coffinier, Susan Michaelis, et al.
Disease Models & Mechanisms|May 26, 2018
ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stabilityEric D Spear, Erh-Ting Hsu, Laiyin Nie, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|May 14, 2026
Prelamin A in an LmnaL648R/L648R Mouse Model Does Not Promote Atherosclerosis or Vascular Smooth Muscle LossYuexia Wang, Leroy C Joseph, Cecilia Östlund, et al.
Chest|September 16, 2005
Fluoroquinolones vs macrolides in the treatment of Legionnaires diseaseMiquel Sabrià, María Luisa Pedro-Botet, Joaquín Gómez, et al.
G3 (Bethesda, Md.)|May 13, 2016
Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in YeastMatthew J Maurer, Eric D Spear, Allen T Yu, et al.
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