Showing results (1-10 of 18) with videos related to
Sort By:
Pageof 2
Current Opinion in Drug Discovery & Development|September 2, 2004
Recent advances in CB1 cannabinoid receptor antagonistsJos H M Lange, Chris G KruseDrug Discovery Today|May 18, 2005
Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonistsJos H M Lange, Chris G KruseChemical Record (New York, N.Y.)|June 20, 2008
Cannabinoid CB1 receptor antagonists in therapeutic and structural perspectivesJos H M Lange, Chris G KruseBioorganic & Medicinal Chemistry Letters|August 25, 2009
Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonistsJos H M Lange, Arnold P den Hartog, Martina A W van der Neut, et al.Journal of Medicinal Chemistry|September 21, 2007
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugsJos H M Lange, Jan-Hendrik Reinders, Jeroen T B M Tolboom, et al.Bioorganic & Medicinal Chemistry Letters|April 6, 2010
Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution patternJos H M Lange, Martina A W van der Neut, Alice J M Borst, et al.Journal of Medicinal Chemistry|January 6, 2010
Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonismJos H M Lange, Hein K A C Coolen, Martina A W van der Neut, et al.Bioorganic & Medicinal Chemistry Letters|December 20, 2017
Spiro-1-benzofuranpiperidinylalkanoic acids as a novel and selective sphingosine S1P5 receptor agonist chemotypeAxel R Stoit, Jos H M Lange, Hein K A C Coolen, et al.European Journal of Medicinal Chemistry|September 3, 2011
Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: design, synthesis, structure-activity relationships, physicochemical properties and biological activityAntoni R Blaazer, Jos H M Lange, Martina A W van der Neut, et al.Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB(1) receptor antagonistsJos H M Lange, Martina A W van der Neut, Arnold P den Hartog, et al.Pageof 2