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Lung Cancer (Amsterdam, Netherlands)|February 21, 2025
ENDOLUNG trial, part II. A phase II study of the Akt/mTOR inhibitor and autophagy inducer ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with squamous non-small cell lung cancerJoaquim Bosch-Barrera, Purificación Estévez-García, Paloma Martín-Martorell, et al.
Autophagy|May 14, 2020
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cellsPau Muñoz-Guardiola, Josefina Casas, Elisabet Megías-Roda, et al.
International Journal of Cancer|January 17, 2020
The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancerAnna López-Plana, Patricia Fernández-Nogueira, Pau Muñoz-Guardiola, et al.
BMC Cancer|July 22, 2024
ENDOLUNG trial. A phase 1/2 study of the Akt/mTOR inhibitor and autophagy inducer Ibrilatazar (ABTL0812) in combination with paclitaxel/carboplatin in patients with advanced/recurrent endometrial cancerAlexandra Leary, Purificación Estévez-García, Renaud Sabatier, et al.
ACS Chemical Biology|August 14, 2018
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and BromodomainsJinhua Wang, Tatiana Erazo, Fleur M Ferguson, et al.
Nature Chemical Biology|April 7, 2020
Discovery of a selective inhibitor of doublecortin like kinase 1Fleur M Ferguson, Behnam Nabet, Srivatsan Raghavan, et al.
The Journal of Experimental Medicine|March 29, 2020
Genetic manipulation of LKB1 elicits lethal metastatic prostate cancerIvana Hermanova, Patricia Zúñiga-García, Alfredo Caro-Maldonado, et al.
Nature|January 14, 2026
Polyamine-dependent metabolic shielding regulates alternative splicingAmaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, et al.
Autophagy|February 26, 2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, et al.
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