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Joseph E Coyle

Showing results (11-20 of 20) with videos related to

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ACS Medicinal Chemistry Letters|July 21, 2015
Fragment-Based Discovery of Potent and Selective DDR1/2 InhibitorsChristopher W Murray, Valerio Berdini, Ildiko M Buck, et al.
Journal of Medicinal Chemistry|December 10, 2016
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA<sub>2</sub>)Alison J-A Woolford, Philip J Day, Véronique Bénéton, et al.
ACS Medicinal Chemistry Letters|January 16, 2015
Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper KinaseChristopher N Johnson, Christophe Adelinet, Valerio Berdini, et al.
Journal of Medicinal Chemistry|April 12, 2019
Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein InteractionTom D Heightman, James F Callahan, Elisabetta Chiarparin, et al.
ACS Chemical Biology|August 30, 2016
Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin DerivativesDominic Tisi, Elisabetta Chiarparin, Emiliano Tamanini, et al.
Journal of Medicinal Chemistry|July 29, 2010
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug designAndrew J Woodhead, Hayley Angove, Maria G Carr, et al.
Journal of Medicinal Chemistry|April 1, 2016
Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based DiscoveryThomas G Davies, William E Wixted, Joseph E Coyle, et al.
Journal of Medicinal Chemistry|May 12, 2016
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment ScreeningAlison J-A Woolford, Joseph E Pero, Sridhar Aravapalli, et al.
Journal of Medicinal Chemistry|June 27, 2024
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-GlucocerebrosidaseNick Palmer, Christopher Agnew, Caroline Benn, et al.
Journal of Medicinal Chemistry|August 13, 2021
Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2Tom D Heightman, Valerio Berdini, Luke Bevan, et al.
Pageof 2

Showing results (11-20 of 20) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 20 results.
ACS Medicinal Chemistry Letters|July 21, 2015
Fragment-Based Discovery of Potent and Selective DDR1/2 InhibitorsChristopher W Murray, Valerio Berdini, Ildiko M Buck, et al.
Journal of Medicinal Chemistry|December 10, 2016
Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA<sub>2</sub>)Alison J-A Woolford, Philip J Day, Véronique Bénéton, et al.
ACS Medicinal Chemistry Letters|January 16, 2015
Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper KinaseChristopher N Johnson, Christophe Adelinet, Valerio Berdini, et al.
Journal of Medicinal Chemistry|April 12, 2019
Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein InteractionTom D Heightman, James F Callahan, Elisabetta Chiarparin, et al.
ACS Chemical Biology|August 30, 2016
Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin DerivativesDominic Tisi, Elisabetta Chiarparin, Emiliano Tamanini, et al.
Journal of Medicinal Chemistry|July 29, 2010
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug designAndrew J Woodhead, Hayley Angove, Maria G Carr, et al.
Journal of Medicinal Chemistry|April 1, 2016
Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based DiscoveryThomas G Davies, William E Wixted, Joseph E Coyle, et al.
Journal of Medicinal Chemistry|May 12, 2016
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment ScreeningAlison J-A Woolford, Joseph E Pero, Sridhar Aravapalli, et al.
Journal of Medicinal Chemistry|June 27, 2024
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-GlucocerebrosidaseNick Palmer, Christopher Agnew, Caroline Benn, et al.
Journal of Medicinal Chemistry|August 13, 2021
Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2Tom D Heightman, Valerio Berdini, Luke Bevan, et al.
Pageof 2