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Regulatory Toxicology and Pharmacology : RTP
|
August 24, 2013
Validation of Toxtree and SciQSAR in silico predictive software using a publicly available benchmark mutagenicity database and their applicability for the qualification of impurities in pharmaceuticals
Joseph F Contrera
Regulatory Toxicology and Pharmacology : RTP
|
October 12, 2010
Improved in silico prediction of carcinogenic potency (TD50) and the risk specific dose (RSD) adjusted Threshold of Toxicological Concern (TTC) for genotoxic chemicals and pharmaceutical impurities
Joseph F Contrera
Expert Opinion on Drug Metabolism & Toxicology
|
February 3, 2007
In silico approaches to explore toxicity end points: issues and concerns for estimating human health effects
Edwin J Matthews, Joseph F Contrera
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 30, 2006
Genetic toxicity assessment: employing the best science for human safety evaluation. Part I: Early screening for potential human mutagens
David Jacobson-Kram, Joseph F Contrera
Regulatory Toxicology and Pharmacology : RTP
|
November 19, 2003
Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices
Joseph F Contrera, Edwin J Matthews, R Daniel Benz
Current Drug Discovery Technologies
|
February 14, 2006
QSAR modeling of carcinogenic risk using discriminant analysis and topological molecular descriptors
Joseph F Contrera, Philip Maclaughlin, Lowell H Hall, et al.
Regulatory Toxicology and Pharmacology : RTP
|
January 9, 2007
A comprehensive model for reproductive and developmental toxicity hazard identification: I. Development of a weight of evidence QSAR database
Edwin J Matthews, Naomi L Kruhlak, R Daniel Benz, et al.
Toxicology and Applied Pharmacology
|
May 8, 2007
Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling
Luis G Valerio, Kirk B Arvidson, Ronald F Chanderbhan, et al.
Regulatory Toxicology and Pharmacology : RTP
|
November 18, 2004
Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose
Joseph F Contrera, Edwin J Matthews, Naomi L Kruhlak, et al.
Regulatory Toxicology and Pharmacology : RTP
|
October 26, 2005
In silico screening of chemicals for bacterial mutagenicity using electrotopological E-state indices and MDL QSAR software
Joseph F Contrera, Edwin J Matthews, Naomi L Kruhlak, et al.
Page
of 3
Search research articles
Search
Showing results (1-10 of 24) with videos related to
Sort By:
Page
of 3
Regulatory Toxicology and Pharmacology : RTP
|
August 24, 2013
Validation of Toxtree and SciQSAR in silico predictive software using a publicly available benchmark mutagenicity database and their applicability for the qualification of impurities in pharmaceuticals
Joseph F Contrera
Regulatory Toxicology and Pharmacology : RTP
|
October 12, 2010
Improved in silico prediction of carcinogenic potency (TD50) and the risk specific dose (RSD) adjusted Threshold of Toxicological Concern (TTC) for genotoxic chemicals and pharmaceutical impurities
Joseph F Contrera
Expert Opinion on Drug Metabolism & Toxicology
|
February 3, 2007
In silico approaches to explore toxicity end points: issues and concerns for estimating human health effects
Edwin J Matthews, Joseph F Contrera
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 30, 2006
Genetic toxicity assessment: employing the best science for human safety evaluation. Part I: Early screening for potential human mutagens
David Jacobson-Kram, Joseph F Contrera
Regulatory Toxicology and Pharmacology : RTP
|
November 19, 2003
Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices
Joseph F Contrera, Edwin J Matthews, R Daniel Benz
Current Drug Discovery Technologies
|
February 14, 2006
QSAR modeling of carcinogenic risk using discriminant analysis and topological molecular descriptors
Joseph F Contrera, Philip Maclaughlin, Lowell H Hall, et al.
Regulatory Toxicology and Pharmacology : RTP
|
January 9, 2007
A comprehensive model for reproductive and developmental toxicity hazard identification: I. Development of a weight of evidence QSAR database
Edwin J Matthews, Naomi L Kruhlak, R Daniel Benz, et al.
Toxicology and Applied Pharmacology
|
May 8, 2007
Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling
Luis G Valerio, Kirk B Arvidson, Ronald F Chanderbhan, et al.
Regulatory Toxicology and Pharmacology : RTP
|
November 18, 2004
Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose
Joseph F Contrera, Edwin J Matthews, Naomi L Kruhlak, et al.
Regulatory Toxicology and Pharmacology : RTP
|
October 26, 2005
In silico screening of chemicals for bacterial mutagenicity using electrotopological E-state indices and MDL QSAR software
Joseph F Contrera, Edwin J Matthews, Naomi L Kruhlak, et al.
Page
of 3