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Frontiers in Toxicology
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August 1, 2025
Stress convulsions in rodents: within a weight-of-evidence framework for human seizure risk
Joseph J DeGeorge, Monica R Metea
Biomarkers in Medicine
|
August 25, 2011
Promise of new translational safety biomarkers in drug development and challenges to regulatory qualification
Frank D Sistare, Joseph J DeGeorge
Methods in Molecular Biology (Clifton, N.J.)
|
May 2, 2008
Applications of toxicogenomics to nonclinical drug development: regulatory science considerations
Frank D Sistare, Joseph J Degeorge
ILAR Journal
|
January 6, 2017
Scientific Knowledge and Technology, Animal Experimentation, and Pharmaceutical Development
Lewis B Kinter, Joseph J DeGeorge
Toxicologic Pathology
|
June 7, 2015
Regulatory Forum Commentary* Counterpoint: Dose Selection for Tg.rasH2 Mouse Carcinogenicity Studies
Jarig Darbes, Frank D Sistare, Joseph J DeGeorge
Regulatory Toxicology and Pharmacology : RTP
|
June 24, 2019
Exposure assessments in reproductive and developmental toxicity testing: An IQ-DruSafe industry survey on current practices and experiences in support of exposure-based high dose selection
Paul A Andrews, Mary Ellen McNerney, Joseph J DeGeorge
ILAR Journal
|
June 28, 2021
A Brief History of Use of Animals in Biomedical Research and Perspective on Non-Animal Alternatives
Lewis B Kinter, Ron DeHaven, David K Johnson, et al.
Toxicologic Pathology
|
November 7, 2009
An industry perspective on the utility of short-term carcinogenicity testing in transgenic mice in pharmaceutical development
Richard D Storer, Frank D Sistare, M Vijayaraj Reddy, et al.
Chemical Research in Toxicology
|
January 28, 2009
Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s
Mark W Powley, Clay B Frederick, Frank D Sistare, et al.
Birth Defects Research. Part B, Developmental and Reproductive Toxicology
|
April 11, 2016
An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors
Frederique M Poulet, Jayanthi J Wolf, Danuta J Herzyk, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 16) with videos related to
Sort By:
Page
of 2
Frontiers in Toxicology
|
August 1, 2025
Stress convulsions in rodents: within a weight-of-evidence framework for human seizure risk
Joseph J DeGeorge, Monica R Metea
Biomarkers in Medicine
|
August 25, 2011
Promise of new translational safety biomarkers in drug development and challenges to regulatory qualification
Frank D Sistare, Joseph J DeGeorge
Methods in Molecular Biology (Clifton, N.J.)
|
May 2, 2008
Applications of toxicogenomics to nonclinical drug development: regulatory science considerations
Frank D Sistare, Joseph J Degeorge
ILAR Journal
|
January 6, 2017
Scientific Knowledge and Technology, Animal Experimentation, and Pharmaceutical Development
Lewis B Kinter, Joseph J DeGeorge
Toxicologic Pathology
|
June 7, 2015
Regulatory Forum Commentary* Counterpoint: Dose Selection for Tg.rasH2 Mouse Carcinogenicity Studies
Jarig Darbes, Frank D Sistare, Joseph J DeGeorge
Regulatory Toxicology and Pharmacology : RTP
|
June 24, 2019
Exposure assessments in reproductive and developmental toxicity testing: An IQ-DruSafe industry survey on current practices and experiences in support of exposure-based high dose selection
Paul A Andrews, Mary Ellen McNerney, Joseph J DeGeorge
ILAR Journal
|
June 28, 2021
A Brief History of Use of Animals in Biomedical Research and Perspective on Non-Animal Alternatives
Lewis B Kinter, Ron DeHaven, David K Johnson, et al.
Toxicologic Pathology
|
November 7, 2009
An industry perspective on the utility of short-term carcinogenicity testing in transgenic mice in pharmaceutical development
Richard D Storer, Frank D Sistare, M Vijayaraj Reddy, et al.
Chemical Research in Toxicology
|
January 28, 2009
Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s
Mark W Powley, Clay B Frederick, Frank D Sistare, et al.
Birth Defects Research. Part B, Developmental and Reproductive Toxicology
|
April 11, 2016
An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors
Frederique M Poulet, Jayanthi J Wolf, Danuta J Herzyk, et al.
Page
of 2