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Genetics|September 11, 2008
A fundamental relationship between genotype frequencies and fitnessesJoseph LachanceBMC Medical Genomics|December 15, 2010
Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectationsJoseph LachanceGenetics, Selection, Evolution : GSE|March 17, 2009
Detecting selection-induced departures from Hardy-Weinberg proportionsJoseph LachanceJournal of Theoretical Biology|August 15, 2009
Inbreeding, pedigree size, and the most recent common ancestor of humanityJoseph LachanceCancer Research|May 18, 2021
Beyond Stamp Collecting: Evolutionary and Functional Genomics Advance Our Understanding of Cancer BiologyJoseph LachanceMolecular Biology and Evolution|June 7, 2026
Limited selection on Neanderthal DNA in 30,780 recently admixed genomes with African-like ancestryAaron Pfennig, Joseph LachanceG3 (Bethesda, Md.)|May 10, 2022
Hybrid fitness effects modify fixation probabilities of introgressed allelesAaron Pfennig, Joseph LachanceBiorxiv : the Preprint Server for Biology|August 2, 2024
The evolutionary fate of Neanderthal DNA in 30,780 admixed genomes with recent African-like ancestryAaron Pfennig, Joseph LachanceAmerican Journal of Human Genetics|February 3, 2023
Challenges of accurately estimating sex-biased admixture from X chromosomal and autosomal ancestry proportionsAaron Pfennig, Joseph LachanceAmerican Journal of Human Genetics|October 4, 2014
Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive allelesJoseph Lachance, Sarah A TishkoffPageof 5