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Joseph P Vacca

Showing results (11-20 of 84) with videos related to

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Bioorganic & Medicinal Chemistry Letters|December 2, 2011
Discovery of pyrrolidine-based β-secretase inhibitors: lead advancement through conformational design for maintenance of ligand binding efficiencyShawn J Stachel, Thomas G Steele, Alessia Petrocchi, et al.
Bioorganic & Medicinal Chemistry Letters|September 21, 2010
Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chiralityMichael R Wood, Kathy M Schirripa, June J Kim, et al.
Bioorganic & Medicinal Chemistry Letters|July 23, 2003
Design and synthesis of potent and selective macrocyclic thrombin inhibitorsPhilippe G Nantermet, James C Barrow, Christina L Newton, et al.
Antimicrobial Agents and Chemotherapy|October 21, 2009
MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A proteaseNigel J Liverton, Steven S Carroll, Jillian Dimuzio, et al.
Bioorganic & Medicinal Chemistry Letters|September 9, 2008
Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integraseJeffrey Y Melamed, Melissa S Egbertson, Sandor Varga, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2011
Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918Daniel V Paone, Diem N Nguyen, Anthony W Shaw, et al.
Bioorganic & Medicinal Chemistry Letters|October 13, 2007
8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitorsThorsten E Fisher, Boyoung Kim, Donnette D Staas, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2007
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitorsKeith P Moore, Hong Zhu, Hemaka A Rajapakse, et al.
Bioorganic & Medicinal Chemistry Letters|September 3, 2005
Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimizationJames Z Deng, Daniel R McMasters, Philippe M A Rabbat, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2007
Calcitonin gene-related peptide (CGRP) receptor antagonists: investigations of a pyridinone templateDiem N Nguyen, Daniel V Paone, Anthony W Shaw, et al.
Pageof 9

Showing results (11-20 of 84) with videos related to

Sort By:
Pageof 9
Bioorganic & Medicinal Chemistry Letters|December 2, 2011
Discovery of pyrrolidine-based β-secretase inhibitors: lead advancement through conformational design for maintenance of ligand binding efficiencyShawn J Stachel, Thomas G Steele, Alessia Petrocchi, et al.
Bioorganic & Medicinal Chemistry Letters|September 21, 2010
Novel CGRP receptor antagonists from central amide replacements causing a reversal of preferred chiralityMichael R Wood, Kathy M Schirripa, June J Kim, et al.
Bioorganic & Medicinal Chemistry Letters|July 23, 2003
Design and synthesis of potent and selective macrocyclic thrombin inhibitorsPhilippe G Nantermet, James C Barrow, Christina L Newton, et al.
Antimicrobial Agents and Chemotherapy|October 21, 2009
MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A proteaseNigel J Liverton, Steven S Carroll, Jillian Dimuzio, et al.
Bioorganic & Medicinal Chemistry Letters|September 9, 2008
Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integraseJeffrey Y Melamed, Melissa S Egbertson, Sandor Varga, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2011
Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918Daniel V Paone, Diem N Nguyen, Anthony W Shaw, et al.
Bioorganic & Medicinal Chemistry Letters|October 13, 2007
8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitorsThorsten E Fisher, Boyoung Kim, Donnette D Staas, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2007
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitorsKeith P Moore, Hong Zhu, Hemaka A Rajapakse, et al.
Bioorganic & Medicinal Chemistry Letters|September 3, 2005
Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimizationJames Z Deng, Daniel R McMasters, Philippe M A Rabbat, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2007
Calcitonin gene-related peptide (CGRP) receptor antagonists: investigations of a pyridinone templateDiem N Nguyen, Daniel V Paone, Anthony W Shaw, et al.
Pageof 9