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Overview Leadership Blog JoVE Help Center

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Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

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JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

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Joseph R Stock

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Bioorganic & Medicinal Chemistry Letters|December 29, 2007

Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pocketsDerek C Cole, Joseph R Stock, Rajiv Chopra, et al.

Bioorganic & Medicinal Chemistry Letters|December 5, 2009

Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitorsPawel Nowak, Derek C Cole, Ann Aulabaugh, et al.

Journal of Medicinal Chemistry|October 13, 2006

Acylguanidines as small-molecule beta-secretase inhibitorsDerek C Cole, Eric S Manas, Joseph R Stock, et al.

Bioorganic & Medicinal Chemistry Letters|June 17, 2008

Discovery of a novel series of Notch-sparing gamma-secretase inhibitorsAnthony Kreft, Boyd Harrison, Suzan Aschmies, et al.

Bioorganic & Medicinal Chemistry Letters|December 23, 2008

(S)-N-(5-Chlorothiophene-2-sulfonyl)-beta,beta-diethylalaninol a Notch-1-sparing gamma-secretase inhibitorDerek C Cole, Joseph R Stock, Anthony F Kreft, et al.

Journal of Medicinal Chemistry|November 18, 2008

Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's diseaseScott C Mayer, Anthony F Kreft, Boyd Harrison, et al.

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Search research articles

Showing results (11-20 of 16) with videos related to

Sort By:

Pageof 2

You have reached the last page of results.This site can display upto 16 results.

Bioorganic & Medicinal Chemistry Letters|December 29, 2007

Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pocketsDerek C Cole, Joseph R Stock, Rajiv Chopra, et al.

Bioorganic & Medicinal Chemistry Letters|December 5, 2009

Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitorsPawel Nowak, Derek C Cole, Ann Aulabaugh, et al.

Journal of Medicinal Chemistry|October 13, 2006

Acylguanidines as small-molecule beta-secretase inhibitorsDerek C Cole, Eric S Manas, Joseph R Stock, et al.

Bioorganic & Medicinal Chemistry Letters|June 17, 2008

Discovery of a novel series of Notch-sparing gamma-secretase inhibitorsAnthony Kreft, Boyd Harrison, Suzan Aschmies, et al.

Bioorganic & Medicinal Chemistry Letters|December 23, 2008

(S)-N-(5-Chlorothiophene-2-sulfonyl)-beta,beta-diethylalaninol a Notch-1-sparing gamma-secretase inhibitorDerek C Cole, Joseph R Stock, Anthony F Kreft, et al.

Journal of Medicinal Chemistry|November 18, 2008

Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's diseaseScott C Mayer, Anthony F Kreft, Boyd Harrison, et al.

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