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Journal of Medicinal Chemistry|March 4, 2011
Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studiesTakashi Yamamoto, Padma Nair, Tally M Largent-Milnes, et al.Brain : a Journal of Neurology|December 4, 2008
Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptorsWenjun Zhang, Shannon Gardell, Dongqin Zhang, et al.European Journal of Medicinal Chemistry|August 10, 2010
Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2Cesare Giordano, Anna Sansone, Annalisa Masi, et al.Pain|July 6, 2010
Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonistMarina Vardanyan, Ohannes K Melemedjian, Theodore J Price, et al.Journal of Medicinal Chemistry|September 30, 2008
The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonistsTakashi Yamamoto, Padma Nair, Neil E Jacobsen, et al.Journal of Medicinal Chemistry|March 8, 2012
The cis-4-amino-L-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analoguesAdriano Mollica, Francesco Pinnen, Azzurra Stefanucci, et al.Journal of Medicinal Chemistry|June 22, 2010
Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonistsTakashi Yamamoto, Padma Nair, Neil E Jacobsen, et al.Bioorganic & Medicinal Chemistry Letters|August 1, 2013
Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activitiesPadma Nair, Takashi Yamamoto, Tally M Largent-Milnes, et al.ACS Nano|February 15, 2021
Modular Imaging Scaffold for Single-Particle Electron MicroscopyNesrine Aissaoui, Josephine Lai-Kee-Him, Allan Mills, et al.Journal of Medicinal Chemistry|March 19, 2011
Design of novel neurokinin 1 receptor antagonists based on conformationally constrained aromatic amino acids and discovery of a potent chimeric opioid agonist-neurokinin 1 receptor antagonistSteven Ballet, Debby Feytens, Koen Buysse, et al.Pageof 12