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Journal of Medicinal Chemistry|February 13, 2008
A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonistsTakashi Yamamoto, Padma Nair, Josef Vagner, et al.Pain|July 13, 2011
Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic painMilena De Felice, Raul Sanoja, Ruizhong Wang, et al.The AAPS Journal|October 10, 2006
New paradigms and tools in drug design for pain and addictionVictor J Hruby, Frank Porreca, Henry I Yamamura, et al.Nature Communications|November 17, 2022
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complexJakub Gruszczyk, Loïc Grandvuillemin, Josephine Lai-Kee-Him, et al.Journal of the American Chemical Society|April 19, 2014
Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cordYeon Sun Lee, Dhanasekaran Muthu, Sara M Hall, et al.European Journal of Pharmacology|February 20, 2008
Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptorsTodd W Vanderah, Tally Largent-Milnes, Josephine Lai, et al.Journal of Molecular Biology|December 22, 2023
Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related CompoundsHok-Sau Kwong, Matteo Paloni, Loïc Grandvuillemin, et al.Brain Research|May 10, 2011
Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic painKatherine E Hanlon, Dave S Herman, Richard S Agnes, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 7, 2008
Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonistsBeatriz Fioravanti, Milena De Felice, Cheryl L Stucky, et al.Biopolymers|July 28, 2007
Opioid and melanocortin receptors: do they have overlapping pharmacophores?Yeon Sun Lee, Richard S Agnes, James P Cain, et al.Pageof 12