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Plos Pathogens|June 2, 2016
Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant DefenseKan Lin, Kathryn M O'Brien, Carolina Trujillo, et al.Nucleic Acids Research|November 16, 2010
Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymeraseJee-Hyun Kim, Jun-Rong Wei, Joshua B Wallach, et al.Antimicrobial Agents and Chemotherapy|June 15, 2016
Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3Wei Li, Andrés Obregón-Henao, Joshua B Wallach, et al.Cell Reports|December 21, 2023
CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosisSteven J Grigsby, G V R Krishna Prasad, Joshua B Wallach, et al.Molecular Microbiology|July 8, 2020
Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell deathAnisha Zaveri, Ruojun Wang, Laure Botella, et al.Mbio|April 20, 2026
Utilization of a CRISPRi-based ex vivo challenge model to reveal temporally dependent gene essentiality in intracellular Mycobacterium tuberculosisMonique E Theriault, Andrew I Wong, Michael A DeJesus, et al.Cell|July 23, 2021
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosisBarbara Bosch, Michael A DeJesus, Nicholas C Poulton, et al.Journal of Medicinal Chemistry|April 22, 2026
Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosisQiang Liu, Curtis A Engelhart, Joshua B Wallach, et al.Proceedings of the National Academy of Sciences of the United States of America|November 6, 2013
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistenceJee-Hyun Kim, Kathryn M O'Brien, Ritu Sharma, et al.Cell Systems|July 30, 2025
Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug actionWilliam C Johnson, Ares Alivisatos, Trever C Smith, et al.Pageof 2