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Chemical Science|May 2, 2025
Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assemblyDietrich Mostert, Josef Braun, Matthew D Zimmerman, et al.Plos Pathogens|March 4, 2014
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infectionAlexandre Gouzy, Gérald Larrouy-Maumus, Daria Bottai, et al.Journal of Medicinal Chemistry|October 24, 2018
Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-OxidaseSangmi Oh, Yumi Park, Curtis A Engelhart, et al.Journal of Medicinal Chemistry|January 17, 2025
Metabolically Stable Adenylation Inhibitors of Biotin Protein Ligase as Antibacterial AgentsQiang Liu, Curtis A Engelhart, Joshua B Wallach, et al.Biorxiv : the Preprint Server for Biology|October 3, 2025
Structure-Guided Development of a Potent BioA Inhibitor Validates Biotin Synthesis Inhibition as a Therapeutic Strategy for TuberculosisQiang Liu, Joshua B Wallach, Yahani P Jayasinghe, et al.ACS Infectious Diseases|May 14, 2026
Identification and Evaluation of Dibasic Piperidines as Cell Wall Inhibitors against Mycobacterium tuberculosisClaire Naylor, Gareth Prosser, Tracy Bayliss, et al.Biorxiv : the Preprint Server for Biology|February 26, 2026
Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against Mycobacterium tuberculosisClaire Naylor, Gareth A Prosser, Tracy Bayliss, et al.Biorxiv : the Preprint Server for Biology|November 28, 2023
Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge ModelXin Wang, Hongwei Su, Joshua B Wallach, et al.Nature Microbiology|January 10, 2025
Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal modelsXin Wang, Hongwei Su, Joshua B Wallach, et al.Nature|June 21, 2019
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classesEachan O Johnson, Emily LaVerriere, Emma Office, et al.Pageof 2