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Molecular Psychiatry|September 21, 2023
CaMKK2 as an emerging treatment target for bipolar disorderJacqueline Kaiser, Kevin Nay, Christopher R Horne, et al.Nature Communications|May 12, 2021
The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradationSwarna L Vijayaraj, Rebecca Feltham, Maryam Rashidi, et al.Nature Communications|November 23, 2021
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosisYanxiang Meng, Katherine A Davies, Cheree Fitzgibbon, et al.Cell Death & Disease|April 2, 2022
The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKLAnnette V Jacobsen, Catia L Pierotti, Kym N Lowes, et al.The EMBO Journal|October 26, 2021
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosisZikou Liu, Laura F Dagley, Kristy Shield-Artin, et al.Cell Reports|November 15, 2018
Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 PathwayNatasha Jansz, Tatyana Nesterova, Andrew Keniry, et al.Journal of Biomolecular Screening|November 17, 2011
An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targetsHendrik Falk, Theresa Connor, Hong Yang, et al.Cell Death and Differentiation|February 3, 2026
The kinase domain of RIPK3 tunes its scaffolding functionsShene Chiou, Christopher R Horne, Komal M Patel, et al.Circulation Research|May 18, 2019
Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 TranscriptionKyuho Jeong, Jung-Hyun Kim, James M Murphy, et al.Nature Communications|June 21, 2020
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologuesKatherine A Davies, Cheree Fitzgibbon, Samuel N Young, et al.Pageof 40