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The Journal of Biological Chemistry
|
December 26, 2021
Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir
Calvin J Gordon, Hery W Lee, Egor P Tchesnokov, et al.
Antimicrobial Agents and Chemotherapy
|
March 30, 2004
Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase
Joy Y Feng, Eisuke Murakami, Suzana M Zorca, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 27, 2012
Synthesis and antiviral activity of a series of 1'-substituted 4-aza-7,9-dideazaadenosine C-nucleosides
Aesop Cho, Oliver L Saunders, Thomas Butler, et al.
Plos One
|
October 12, 2017
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs
Ona Barauskas, Weimei Xing, Esmeralda Aguayo, et al.
Microbiology Spectrum
|
November 19, 2024
Lack of activity of HIV-1 integrase strand-transfer inhibitors on recombinase activating gene (RAG) activity at clinically relevant concentrations
Sally Demirdjian, Vincent N Duong, Jennifer N Byrum, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2013
Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase
Jay P Parrish, Sharon K Lee, Constantine G Boojamra, et al.
The Journal of Biological Chemistry
|
June 30, 2024
Mechanism and spectrum of inhibition of a 4'-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses
Calvin J Gordon, Simon M Walker, Egor P Tchesnokov, et al.
Plos One
|
August 16, 2017
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors
Weimei Xing, Ona Barauskas, Thorsten Kirschberg, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 8, 2014
Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors
Michael R Mish, Aesop Cho, Thorsten Kirschberg, et al.
Journal of Acquired Immune Deficiency Syndromes (1999)
|
July 11, 2008
The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation
Evguenia S Svarovskaia, Joy Y Feng, Nicolas A Margot, et al.
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Search research articles
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Showing results (21-30 of 76) with videos related to
Sort By:
Page
of 8
The Journal of Biological Chemistry
|
December 26, 2021
Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir
Calvin J Gordon, Hery W Lee, Egor P Tchesnokov, et al.
Antimicrobial Agents and Chemotherapy
|
March 30, 2004
Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase
Joy Y Feng, Eisuke Murakami, Suzana M Zorca, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 27, 2012
Synthesis and antiviral activity of a series of 1'-substituted 4-aza-7,9-dideazaadenosine C-nucleosides
Aesop Cho, Oliver L Saunders, Thomas Butler, et al.
Plos One
|
October 12, 2017
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs
Ona Barauskas, Weimei Xing, Esmeralda Aguayo, et al.
Microbiology Spectrum
|
November 19, 2024
Lack of activity of HIV-1 integrase strand-transfer inhibitors on recombinase activating gene (RAG) activity at clinically relevant concentrations
Sally Demirdjian, Vincent N Duong, Jennifer N Byrum, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2013
Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase
Jay P Parrish, Sharon K Lee, Constantine G Boojamra, et al.
The Journal of Biological Chemistry
|
June 30, 2024
Mechanism and spectrum of inhibition of a 4'-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses
Calvin J Gordon, Simon M Walker, Egor P Tchesnokov, et al.
Plos One
|
August 16, 2017
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors
Weimei Xing, Ona Barauskas, Thorsten Kirschberg, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 8, 2014
Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors
Michael R Mish, Aesop Cho, Thorsten Kirschberg, et al.
Journal of Acquired Immune Deficiency Syndromes (1999)
|
July 11, 2008
The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation
Evguenia S Svarovskaia, Joy Y Feng, Nicolas A Margot, et al.
Page
of 8