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Journal of Medicinal Chemistry
|
August 16, 2019
Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases
Janina Niggenaber, Julia Hardick, Jonas Lategahn, et al.
Angewandte Chemie (International Ed. in English)
|
August 24, 2017
Covalent Lipid Pocket Ligands Targeting p38α MAPK Mutants
Mike Bührmann, Julia Hardick, Jörn Weisner, et al.
Plos One
|
September 12, 2017
Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK
Mike Bührmann, Bianca M Wiedemann, Matthias P Müller, et al.
Journal of Medicinal Chemistry
|
February 16, 2019
Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors
Patrik Wolle, Julia Hardick, Shane J F Cronin, et al.
Journal of Medicinal Chemistry
|
October 10, 2017
Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT
Helena Kaitsiotou, Marina Keul, Julia Hardick, et al.
Journal of Medicinal Chemistry
|
January 22, 2025
Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST
Tom Schulz, Rajesh Gontla, Alina Teuber, et al.
Chemical Science
|
April 19, 2019
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt
Niklas Uhlenbrock, Steven Smith, Jörn Weisner, et al.
Journal of Medicinal Chemistry
|
August 1, 2022
Optimization of Covalent MKK7 Inhibitors <i>via</i> Crude Nanomole-Scale Libraries
Paul Gehrtz, Shir Marom, Mike Bührmann, et al.
Journal of Medicinal Chemistry
|
September 15, 2020
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach
Jonas Lategahn, Julia Hardick, Tobias Grabe, et al.
Chemical Science
|
December 21, 2019
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S
Jonas Lategahn, Marina Keul, Philip Klövekorn, et al.
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Search research articles
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Showing results (1-10 of 11) with videos related to
Sort By:
Page
of 2
Journal of Medicinal Chemistry
|
August 16, 2019
Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases
Janina Niggenaber, Julia Hardick, Jonas Lategahn, et al.
Angewandte Chemie (International Ed. in English)
|
August 24, 2017
Covalent Lipid Pocket Ligands Targeting p38α MAPK Mutants
Mike Bührmann, Julia Hardick, Jörn Weisner, et al.
Plos One
|
September 12, 2017
Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK
Mike Bührmann, Bianca M Wiedemann, Matthias P Müller, et al.
Journal of Medicinal Chemistry
|
February 16, 2019
Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors
Patrik Wolle, Julia Hardick, Shane J F Cronin, et al.
Journal of Medicinal Chemistry
|
October 10, 2017
Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT
Helena Kaitsiotou, Marina Keul, Julia Hardick, et al.
Journal of Medicinal Chemistry
|
January 22, 2025
Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST
Tom Schulz, Rajesh Gontla, Alina Teuber, et al.
Chemical Science
|
April 19, 2019
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt
Niklas Uhlenbrock, Steven Smith, Jörn Weisner, et al.
Journal of Medicinal Chemistry
|
August 1, 2022
Optimization of Covalent MKK7 Inhibitors <i>via</i> Crude Nanomole-Scale Libraries
Paul Gehrtz, Shir Marom, Mike Bührmann, et al.
Journal of Medicinal Chemistry
|
September 15, 2020
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach
Jonas Lategahn, Julia Hardick, Tobias Grabe, et al.
Chemical Science
|
December 21, 2019
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S
Jonas Lategahn, Marina Keul, Philip Klövekorn, et al.
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of 2