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Current Atherosclerosis Reports|September 13, 2013
New insights into modulation of thrombin formationHenri M H Spronk, Julian I Borissoff, Hugo ten Cate
JACC. Cardiovascular Imaging|December 15, 2012
Accelerated in vivo thrombin formation independently predicts the presence and severity of CT angiographic coronary atherosclerosisJulian I Borissoff, Ivo A Joosen, Mathijs O Versteylen, et al.
Blood|November 9, 2013
VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in miceAlexander S Savchenko, Julian I Borissoff, Kimberly Martinod, et al.
The Journal of Pediatrics|March 9, 2026
Macitentan vs Standard of Care in Pediatric Pulmonary Arterial Hypertension (TOMORROW): A Randomized Clinical TrialRolf M F Berger, D Dunbar Ivy, Julian I Borissoff, et al.
The European Respiratory Journal|September 26, 2024
Efficacy and safety of selexipag in patients with inoperable or persistent/recurrent CTEPH (SELECT randomised trial)Nick H Kim, Richard Channick, Marion Delcroix, et al.
Chest|December 22, 2025
A prospective, multicenter, open-label, single-arm Phase 2 study to investigate the pharmacokinetics, safety, tolerability, and exploratory efficacy of selexipag in children with pulmonary arterial hypertensionMaurice Beghetti, Lene Nygaard Axelsen, Julian I Borissoff, et al.
Blood|August 11, 2011
Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrinJoke Konings, José W P Govers-Riemslag, Helen Philippou, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|July 3, 2013
Elevated levels of circulating DNA and chromatin are independently associated with severe coronary atherosclerosis and a prothrombotic stateJulian I Borissoff, Ivo A Joosen, Mathijs O Versteylen, et al.
Plos One|February 15, 2013
Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent mannerJulian I Borissoff, Jeroen J T Otten, Sylvia Heeneman, et al.
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