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Drug Discovery Today|October 2, 2009
HTS and hit finding in academia--from chemical genomics to drug discoveryJulie A Frearson, Iain T CollieCurrent Topics in Medicinal Chemistry|March 16, 2011
Finding new hits in neglected disease projects: target or phenotypic based screening?Ian H Gilbert, Didier Leroy, Julie A FrearsonTrends in Parasitology|October 27, 2007
Target assessment for antiparasitic drug discoveryJulie A Frearson, Paul G Wyatt, Ian H Gilbert, et al.Journal of Medicinal Chemistry|September 9, 2014
The design and synthesis of potent and selective inhibitors of Trypanosoma brucei glycogen synthase kinase 3 for the treatment of human african trypanosomiasisRobert Urich, Raffaella Grimaldi, Torsten Luksch, et al.Plos One|May 8, 2012
IspE inhibitors identified by a combination of in silico and in vitro high-throughput screeningNaomi Tidten-Luksch, Raffaella Grimaldi, Leah S Torrie, et al.Biochemical Pharmacology|August 11, 2010
Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasisDeuan C Jones, Irene Hallyburton, Laste Stojanovski, et al.Analytical Biochemistry|September 15, 2009
Development and validation of a cytochrome c-coupled assay for pteridine reductase 1 and dihydrofolate reductaseEmma J Shanks, Han B Ong, David A Robinson, et al.Bioorganic & Medicinal Chemistry|November 4, 2010
Acetazolamide-based fungal chitinase inhibitorsAlexander W Schüttelkopf, Ludovic Gros, David E Blair, et al.Chemmedchem|June 27, 2009
Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductaseStephen Patterson, Deuan C Jones, Emma J Shanks, et al.Chemmedchem|December 14, 2011
Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitorsDaniel Spinks, Leah S Torrie, Stephen Thompson, et al.Pageof 4