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Journal of Medicinal Chemistry|June 17, 2009
One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screeningChidochangu P Mpamhanga, Daniel Spinks, Lindsay B Tulloch, et al.Chemmedchem|September 14, 2011
Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3Laura A T Cleghorn, Andrew Woodland, Iain T Collie, et al.Journal of Medicinal Chemistry|November 11, 2017
Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase InhibitorsTracy Bayliss, David A Robinson, Victoria C Smith, et al.Chemmedchem|August 12, 2011
Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488Victoria C Smith, Laura A T Cleghorn, Andrew Woodland, et al.Journal of Medicinal Chemistry|September 30, 2015
Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma bruceiLaura A T Cleghorn, Sébastien Albrecht, Laste Stojanovski, et al.The Biochemical Journal|September 22, 2010
High-content screening of feeder-free human embryonic stem cells to identify pro-survival small moleculesPaul D Andrews, Melissa Becroft, Anders Aspegren, et al.Chemmedchem|September 19, 2015
Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase LibraryAndrew Woodland, Stephen Thompson, Laura A T Cleghorn, et al.Chemmedchem|September 24, 2015
Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding ModeDaniel Spinks, Victoria Smith, Stephen Thompson, et al.Journal of Medicinal Chemistry|September 13, 2018
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase InhibitorsJustin R Harrison, Stephen Brand, Victoria Smith, et al.Journal of Medicinal Chemistry|December 14, 2011
Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitorsStephen Brand, Laura A T Cleghorn, Stuart P McElroy, et al.Pageof 4