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Neurobiology of Aging|April 24, 2025
Calpain and caspase regulate Aβ peptide production via cleavage of KINDLIN2 encoded by the AD-associated gene FERMT2Chloé Najdek, Pauline Walle, Amandine Flaig, et al.Acta Neuropathologica Communications|September 24, 2015
Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domainYoann Sottejeau, Alexis Bretteville, François-Xavier Cantrelle, et al.Acta Neuropathologica Communications|January 9, 2022
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defectsErwan Lambert, Orthis Saha, Bruna Soares Landeira, et al.Acta Neuropathologica|May 9, 2019
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr<sup>348</sup> phosphorylationMaxime Sartori, Tiago Mendes, Shruti Desai, et al.Molecular Psychiatry|November 4, 2020
Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent mannerFanny Eysert, Audrey Coulon, Emmanuelle Boscher, et al.Science Advances|May 8, 2021
Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cellsDespoina Kerselidou, Bushra Saeed Dohai, David R Nelson, et al.Ebiomedicine|June 23, 2016
ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's DiseaseFlorent Letronne, Geoffroy Laumet, Anne-Marie Ayral, et al.Acta Neuropathologica|December 10, 2016
Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolismJulien Chapuis, Amandine Flaig, Benjamin Grenier-Boley, et al.Biorxiv : the Preprint Server for Biology|April 3, 2026
Non-microglial downregulation of <i>PLCG2</i> impairs synaptic function and elicits Alzheimer disease-related hallmarksAudrey Coulon, Florian Rabiller, Mari Takalo, et al.Nature Genetics|April 5, 2022
New insights into the genetic etiology of Alzheimer's disease and related dementiasCéline Bellenguez, Fahri Küçükali, Iris E Jansen, et al.Pageof 3