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Expert Opinion on Therapeutic Patents|December 15, 2016
Therapeutic applications of the versatile fatty acid mimetic WY14643Julius Pollinger, Daniel MerkChemmedchem|May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα ModulatorJulius Pollinger, Simone Schierle, Sebastian Neumann, et al.International Journal of Molecular Sciences|November 14, 2020
Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR IsoformsApirat Chaikuad, Julius Pollinger, Michael Rühl, et al.Journal of Medicinal Chemistry|July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ ActivatorsSimone Schierle, Sebastian Neumann, Pascal Heitel, et al.ACS Medicinal Chemistry Letters|September 19, 2019
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer PreferencesJulius Pollinger, Simone Schierle, Leonie Gellrich, et al.Scientific Reports|May 3, 2018
Allosteric modulation of the farnesoid X receptor by a small moleculeMatthias Gabler, Jan Kramer, Jurema Schmidt, et al.Chemmedchem|December 7, 2020
Systematic Assessment of Fragment Identification for Multitarget Drug DesignSteffen Brunst, Jan S Kramer, Whitney Kilu, et al.Communications Chemistry|January 27, 2023
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in micePascal Heitel, Giuseppe Faudone, Moritz Helmstädter, et al.Journal of Medicinal Chemistry|February 1, 2019
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor ModulationJulius Pollinger, Leonie Gellrich, Simone Schierle, et al.Journal of Medicinal Chemistry|January 18, 2024
Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical PropertiesMax Lewandowski, Melania Carmina, Loris Knümann, et al.Pageof 2