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Chemmedchem|May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα ModulatorJulius Pollinger, Simone Schierle, Sebastian Neumann, et al.Journal of Medicinal Chemistry|July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ ActivatorsSimone Schierle, Sebastian Neumann, Pascal Heitel, et al.ACS Medicinal Chemistry Letters|September 19, 2019
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer PreferencesJulius Pollinger, Simone Schierle, Leonie Gellrich, et al.Journal of Medicinal Chemistry|February 1, 2019
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor ModulationJulius Pollinger, Leonie Gellrich, Simone Schierle, et al.Chemmedchem|October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor ModulatorsSimone Schierle, Jurema Schmidt, Astrid Kaiser, et al.Bioorganic & Medicinal Chemistry|July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonistsJurema Schmidt, Simone Schierle, Leonie Gellrich, et al.Communications Chemistry|January 27, 2023
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in micePascal Heitel, Giuseppe Faudone, Moritz Helmstädter, et al.Expert Opinion on Therapeutic Patents|December 15, 2016
Therapeutic applications of the versatile fatty acid mimetic WY14643Julius Pollinger, Daniel MerkMethods in Molecular Biology (Clifton, N.J.)|July 25, 2018
Development of Nuclear Receptor ModulatorsSimone Schierle, Daniel MerkExpert Opinion on Therapeutic Patents|July 13, 2019
Therapeutic modulation of retinoid X receptors - SAR and therapeutic potential of RXR ligands and recent patentsSimone Schierle, Daniel MerkPageof 22