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Molecular Carcinogenesis|April 19, 2017
The nuclear orphan receptor NR4A1 regulates β1-integrin expression in pancreatic and colon cancer cells and can be targeted by NR4A1 antagonistsErik Hedrick, Syng-Ook Lee, Stephen SafeChemico-Biological Interactions|November 13, 2004
Lack of antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin's (TCDDs) induction of cytochrome P4501A1 (CYP1A1) by the putative selective aryl hydrocarbon receptor modulator 6-alkyl-1,3,8-trichlorodibenzofuran (6-MCDF) in the mouse hepatoma cell line Hepa-1c1c7Adrian J Fretland, Stephen Safe, Oliver HankinsonCritical Reviews in Toxicology|June 30, 2020
Ah receptor ligands and their impacts on gut resilience: structure-activity effectsStephen Safe, Arul Jayaraman, Robert S ChapkinCurrent Opinion in Toxicology|May 2, 2017
The Aryl Hydrocarbon Receptor (AhR) as a Drug Target for Cancer ChemotherapyStephen Safe, Yating Cheng, Un-Ho JinBiochemical Pharmacology|March 13, 2012
Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3'-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cellsXi Li, Syng-Ook Lee, Stephen SafeFrontiers in Oncology|April 9, 2013
Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cellsJuliana Vélez, Numsen Hail, Marina Konopleva, et al.Blood|October 30, 2008
CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressureMichael Fiegl, Ismael Samudio, Karen Clise-Dwyer, et al.Cancer Research|November 20, 2016
PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1Alexandra Lacey, Aline Rodrigues-Hoffman, Stephen SafeCancer Medicine|March 5, 2020
Oncolytic virotherapy in hepato-bilio-pancreatic cancer: The key to breaking the log jam?Yuwei Li, Yinan Shen, Ronghua Zhao, et al.Journal of Vascular Research|September 13, 2005
Inhibition of tumor-necrosis-factor-alpha induced endothelial cell activation by a new class of PPAR-gamma agonists. An in vitro study showing receptor-independent effectsPaolo Calabrò, Ismael Samudio, Stephen H Safe, et al.Pageof 247