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The Journal of Steroid Biochemistry and Molecular Biology|October 20, 2007
Inactivation of recombinant human steroid sulfatase by KW-2581Hiroyuki Ishida, Natsuko Sato, Jun Hosogi, et al.Journal of Pharmacokinetics and Pharmacodynamics|October 9, 2022
A quantitative systems pharmacology model for simulating OFF-Time in augmentation trials for Parkinson's disease: application to preladenantRachel Rose, Emma Mitchell, Piet Van Der Graaf, et al.Drug Metabolism and Pharmacokinetics|July 29, 2017
Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in humanJun Hosogi, Rui Ohashi, Hiroshi Maeda, et al.Bioanalysis|December 16, 2017
Immunogenicity of therapeutic protein products: current considerations for anti-drug antibody assay in JapanAkiko Ishii-Watabe, Hiroko Shibata, Kazuko Nishimura, et al.Biopharmaceutics & Drug Disposition|February 17, 2018
An iminium ion metabolite hampers the production of the pharmacologically active metabolite of a multikinase inhibitor KW-2449 in primates: irreversible inhibition of aldehyde oxidase and covalent binding with endogenous proteinsJun Hosogi, Rui Ohashi, Hiroshi Maeda, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|August 25, 2009
LC-MS/MS coupled with immunoaffinity extraction for determination of estrone, 17beta-estradiol and estrone 3-sulfate in human plasmaJun Hosogi, Hideyuki Tanaka, Kazuhiro Fujita, et al.Bioanalysis|September 11, 2018
The ninth Japan Bioanalysis Forum symposiumJunji Komaba, Jun Hosogi, Harue Igarashi, et al.Bioanalysis|August 9, 2019
The 10th Japan Bioanalysis Forum Symposium conference: a reportYoshihisa Sano, Yoshiaki Ohtsu, Harue Igarashi, et al.Bioanalysis|April 5, 2019
Elucidation of the statistical factors that influence anti-drug antibody cut point setting through a multi-laboratory studyKazuko Nishimura, Hiroko Shibata, Muneo Aoyama, et al.Drug Metabolism and Pharmacokinetics|April 4, 2018
Collaborative study using common samples to evaluate the performance of anti-drug antibody assays constructed by different companiesShingo Niimi, Kazuhiro Nishimiya, Masanobu Nishidate, et al.Pageof 1