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Journal of Experimental Neuroscience|December 22, 2018
Is the History Repeated? Can (2R,6R)-Hydroxynorketamine be Another Antidepressant?Shigeyuki Chaki, Jun-Ichi YamaguchiFEBS Open Bio|June 1, 2021
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex IIChieko Kasami, Jun-Ichi Yamaguchi, Hideki InoueAnalytical Biochemistry|October 13, 2012
A surrogate analyte method to determine D-serine in mouse brain using liquid chromatography-tandem mass spectrometryKohnosuke Kinoshita, Shigeji Jingu, Jun-ichi YamaguchiJournal of Pharmaceutical Sciences|October 14, 2015
Impact of Humidity on In Vitro Human Skin Permeation Experiments for Predicting In Vivo PermeabilityMasahiro Ishida, Hiroyuki Takeuchi, Hiromi Endo, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 17, 2022
Bottom-up physiologically based pharmacokinetic modelling for predicting the human pharmacokinetic profiles of the ester prodrug MGS0274 and its active metabolite MGS0008, a metabotropic glutamate 2/3 receptor agonistMotoki Ochi, Kohnosuke Kinoshita, Jun-Ichi Yamaguchi, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 13, 2022
Elucidation of clearance mechanism of TP0463518, a novel hypoxia-inducible factor prolyl hydroxylase inhibitor: does a species difference in excretion routes exist between humans and animals?Hiroki Takano, Akiko Mizuno-Yasuhira, Jun-Ichi Yamaguchi, et al.Biomedical Chromatography : BMC|April 8, 2014
A sensitive and selective method for the quantitative analysis of miglitol in rat plasma using unique solid-phase extraction coupled with liquid chromatography-tandem mass spectrometryAkiko Mizuno-Yasuhira, Kohnosuke Kinoshita, Shigeji Jingu, et al.Journal of Pharmaceutical and Biomedical Analysis|November 11, 2017
A rapid and sensitive chiral LC-MS/MS method for the determination of ketamine and norketamine in mouse plasma, brain and cerebrospinal fluid applicable to the stereoselective pharmacokinetic study of ketamineHidetoh Toki, Takuya Ichikawa, Akiko Mizuno-Yasuhira, et al.Journal of Pharmaceutical and Biomedical Analysis|December 6, 2022
Chiral LC-MS/MS method for the simultaneous determination of (R,S)-ketamine, (R,S)-norketamine, and (2R,6R;2S,6S)-hydroxynorketamine in mouse plasma and brainHidetoh Toki, Jun-Ichi Yamaguchi, Akiko Mizuno-Yasuhira, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|September 21, 2015
Development, validation, and application of a surrogate analyte method for determining N-acetyl-l-aspartyl-l-glutamic acid levels in rat brain, plasma, and cerebrospinal fluidKohnosuke Kinoshita, Kotaro Arai, Kazuaki Kawaura, et al.Pageof 5