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Junliang Hao

Showing results (21-30 of 27) with videos related to

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Journal of Medicinal Chemistry|January 20, 2018
Synthesis and Pharmacological Characterization of C4<sub>β</sub>-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu<sub>3</sub> Receptor AgonistJames A Monn, Steven S Henry, Steven M Massey, et al.
Bioorganic & Medicinal Chemistry Letters|February 5, 2013
Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulatorJunliang Hao, Veronique Dehlinger, Adam M Fivush, et al.
Neuropharmacology|November 6, 2017
Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disordersRobert F Bruns, Stephen N Mitchell, Keith A Wafford, et al.
Journal of Medicinal Chemistry|August 28, 2015
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor AgonistJames A Monn, Lourdes Prieto, Lorena Taboada, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 5, 2016
An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or TachyphylaxisKjell A Svensson, Beverly A Heinz, John M Schaus, et al.
Journal of Medicinal Chemistry|January 21, 2015
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structuresJames A Monn, Lourdes Prieto, Lorena Taboada, et al.
Journal of Medicinal Chemistry|September 19, 2019
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1<i>S</i>,3<i>R</i>)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1<i>H</i>)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 ReceptorJunliang Hao, James P Beck, John M Schaus, et al.
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Showing results (21-30 of 27) with videos related to

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You have reached the last page of results.This site can display upto 27 results.
Journal of Medicinal Chemistry|January 20, 2018
Synthesis and Pharmacological Characterization of C4<sub>β</sub>-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1 S,2 S,4 S,5 R,6 S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2794193), a Highly Potent and Selective mGlu<sub>3</sub> Receptor AgonistJames A Monn, Steven S Henry, Steven M Massey, et al.
Bioorganic & Medicinal Chemistry Letters|February 5, 2013
Discovery of (1R,2R)-N-(4-(6-isopropylpyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide, a potent and orally efficacious mGlu5 receptor negative allosteric modulatorJunliang Hao, Veronique Dehlinger, Adam M Fivush, et al.
Neuropharmacology|November 6, 2017
Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disordersRobert F Bruns, Stephen N Mitchell, Keith A Wafford, et al.
Journal of Medicinal Chemistry|August 28, 2015
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor AgonistJames A Monn, Lourdes Prieto, Lorena Taboada, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 5, 2016
An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or TachyphylaxisKjell A Svensson, Beverly A Heinz, John M Schaus, et al.
Journal of Medicinal Chemistry|January 21, 2015
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structuresJames A Monn, Lourdes Prieto, Lorena Taboada, et al.
Journal of Medicinal Chemistry|September 19, 2019
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1<i>S</i>,3<i>R</i>)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1<i>H</i>)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 ReceptorJunliang Hao, James P Beck, John M Schaus, et al.
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